Postdoctoral Positions — Neurodegenerative Diseases & Mitochondrial Biology

Case Western Reserve University School of Medicine-Faculty of Physiology & Biophysics; Oklahoma; Presencial; USD 52.000 - 66.000; Jornada completa

Descripción de la vacante

Case Western Reserve University School of Medicine, Faculty of Physiology & Biophysics, invites postdoctoral fellows to explore the molecular mechanisms underlying neurodegenerative disorders such as Alzheimer's, Parkinson's, and ALS. The lab investigates how mitochondrial dysfunction and metabolic dysregulation drive disease progression.

Our multidisciplinary program combines patient-derived iPSC neuronal models, transgenic and disease-relevant animal models, and studies in molecular, cellular,

Formación

• PhD and/or MD in neuroscience or related field.
• Experience in neurodegenerative disease, mitochondrial biology, iPSC models, or transgenic mouse models is desirable.
• Strong motivation and ability to work independently and in a team.

Responsabilidades

• Lead projects investigating molecular mechanisms of mitochondrial damage in neurodegenerative diseases.
• Contribute to development of disease-modifying therapeutic approaches.
• Publish findings and present at seminars and conferences.

Conocimientos

Neuroscience research

Mitochondrial biology

iPSC models

Transgenic mouse models

Educación

PhD in neuroscience

MD in neuroscience or related field

Biochemistry / molecular biology / pharmacology

Descripción del empleo

We are recruiting highly motivated postdoctoral fellows to join our laboratory and investigate the molecular mechanisms underlying Alzheimer's disease, Parkinson's disease, ALS, and related neurodegenerative disorders.

Our research focuses on how mitochondrial dysfunction, metabolic dysregulation, and cellular stress contribute to neurodegeneration, with the ultimate goal of identifying new therapeutic strategies.

Our multidisciplinary research program combines:

• Patient-derived iPSC neuronal models
• Transgenic and disease-relevant animal models
• Molecular, cellular, and mitochondrial biology Metabolism, mito-immune and neurodegeneration
• Therapeutic discovery and development, including rationally designed peptide inhibitors of protein-protein interactions and high-throughput screening for mitochondrial functional enhancers.

Successful candidates will have the opportunity to lead projects investigating the molecular basis of mitochondrial damage and metabolic dysfunction in neurodegenerative diseases, while contributing to the development of new disease-modifying therapeutic approaches.

We are looking for candidates with a PhD and/or MD in neuroscience, molecular biology, cell biology, pharmacology, biochemistry, or a related field. Experience in neurodegenerative disease, mitochondrial biology, iPSC models, or transgenic mouse models is particularly desirable.

If you are passionate about understanding the mechanisms of neurodegeneration and translating fundamental discoveries into new therapeutic strategies, we would love to hear from you.