Postdoctoral Associate, Structural Biology Department

University at Buffalo

Town of Amherst (NY)

On-site

USD 55,000 - 65,000

Full time

14 days+

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Job summary

University at Buffalo is seeking a Postdoctoral Associate in the Structural Biology Department for an NIH-funded project led by Prof. Andrew Gulick. The role focuses on protein production, structural biology, and biochemical assay development to explore bacterial natural product biosynthesis.

You will contribute to publications and collaborate across disciplines. The successful candidate will apply X-ray crystallography or cryo-EM to determine structures, analyze data, and help advance

Qualifications

  • PhD in Biochemistry, Chemistry, or related field.
  • Background in protein biochemistry, enzymology, biophysical analysis, or structural biology.
  • Ability to analyze, publish, and present research data.
  • Self-motivation and ability to work independently and as part of a team.

Responsibilities

  • protein production, purification, and analysis, including development and implementation of biochemical assays
  • informatic and genome mining to identify, characterize, and understand the diverse biosynthetic pathways of bacterial sources
  • protein structure determination through X-ray crystallography and/or cryo-electron microscopy and single particle analysis
  • Data analysis, maintenance, and interpretation, including contributions on authoring publications and dissemination of research

Skills

Protein biochemistry
Biochemistry
Analytical skills
Independent & collaborative work

Education

PhD in Biochemistry or related field

Tools

LC-MS
HPLC
Protein structure analysis software
Cryo-EM data analysis

Job description

Postdoctoral Associate, Structural Biology Department
Position Information

Position Title: Postdoctoral Associate, Structural BiologyDepartment

Department: Structural Biology Department

Posting Link: https://apptrkr.com/9854638 https://www.ubjobs.buffalo.edu/postings/64378

Job Type: Full-Time

Position Detail Information
Position Summary

A Postdoctoral Research Associate position isavailable for an NIH-funded position in the lab of Prof. AndrewGulick within the Department of Structural Biology, Jacobs Schoolof Medicine and Biomedical Sciences, University at Buffalo.

The Gulick Lab investigates the structural enzymology of proteinsinvolved in the biosynthesis of bacterial natural products. Throughcombinations of structural biology, biochemical characterization,protein engineering, and biocatalysis, we aim to explore theability of bacteria to produce diverse small molecules that areproduced to help them adapt to the challenges of surviving indiverse environments.

The postdoctoral associate will be responsible for:
  • protein production, purification, and analysis, includingdevelopment and implementation of biochemical assays
  • informatic and genome mining to identify, characterize, andunderstand the diverse biosynthetic pathways of bacterialsources
  • protein structure determination through X-ray crystallographyand/or cryo-electron microscopy and single particle analysis
  • Data analysis, maintenance, and interpretation, includingcontributions on authoring publications and disseminationofresearch
Learn more:
  • Our benefits, where we prioritize your well-beingand success to enhance every aspect of your life.
  • Being a part of the University at Buffalocommunity.

As an Equal Opportunity / Affi theResearch Foundation will not discriminate in its employmentpractices due to an applicant's race, color, religion, sex, sexualorientation, gender identity, national origin and veteran ordisability status.

Minimum Qualifications
  • PhD in Biochemistry, Chemistry, or related field
  • Background in protein biochemistry, enzymology, biophysicalanalysis, or structural biology
  • Ability to analyze, publish, and present research data
  • Self-motivation, ability to work both independently andcollaboratively as a team. Ability to manage time and organizationon multiple projects
Preferred Qualifications
  • Interest in natural product biosynthesis, including pathwayreconstitution, genetic manipulation, small molecule isolation andcharacterization
  • Expertise in enzymology, including assay development, LC-MS andHPLC analysis
  • Experience with X-ray crystallographic analysis and proteinstructure determination or single particle cryo-electron microscopystructure determination and analysis
  • Familiarity with computation tools for protein structuredetermination and analysis.
Salary Range

$55,000 - $65,000

Is a background check required for this posting?

No

Contact Information

Contact's Name: Andrew Gulick

Contact's Pronouns:

Contact's Title: Professor

Contact's Email: amgulick@buffalo.edu

Contact's Phone: 716-829-3696

Posting Dates

Posted: 09/25/2026

Deadline for Applicants:

Date to be filled:

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