Postdoctoral Associate, Structural Biology Department

AgUpdate; Buffalo (NY); On-site; USD 55,000 - 65,000; Full time

Job summary

The University at Buffalo invites applications for a Postdoctoral Associate in the Structural Biology Department, led by Prof. Andrew Gulick. This NIH-funded position focuses on the structural enzymology of biosynthetic enzymes involved in bacterial natural product pathways.

The role encompasses protein production, purification, biochemical assays, and structural determination via X-ray crystallography or cryo-EM, with data analysis and authorship on publications in a collaborative lab setting.

Qualifications

• PhD in Biochemistry, Chemistry, or related field.
• Background in protein biochemistry, enzymology, biophysical analysis, or structural biology.
• Ability to analyze, publish, and present research data.
• Self-motivation and ability to work independently and in a team.
• Time management and organization across multiple projects.

Responsibilities

• Protein production, purification, and analysis including development of biochemical assays.
• Informatic and genome mining to identify and characterize biosynthetic pathways from bacterial sources.
• Protein structure determination by X-ray crystallography and/or cryo-electron microscopy and single particle analysis.
• Data analysis, maintenance, and interpretation with contributions to publications and dissemination of research.

Skills

Protein biochemistry

Enzymology

Biophysical analysis

Structural biology

Publication and presentation

Independent and collaborative work

Time management

Education

PhD in Biochemistry or Chemistry

Tools

X-ray crystallography

Cryo-EM

Computational protein analysis

Job description

Postdoctoral Associate, Structural Biology Department

Position Information

• Position Title: Postdoctoral Associate, Structural Biology Department
• Department: Structural Biology Department
• Posting Link: https://www.ubjobs.buffalo.edu/postings/64378
• Job Type: Full-Time

Position Summary

A Postdoctoral Research Associate position is available for an NIH-funded position in the lab of Prof. Andrew Gulick within the Department of Structural Biology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo.

The Gulick Lab investigates the structural enzymology of proteins involved in the biosynthesis of bacterial natural products. Through combinations of structural biology, biochemical characterization, protein engineering, and biocatalysis, we aim to explore the ability of bacteria to produce diverse small molecules that are produced to help them adapt to the challenges of surviving in diverse environments.

Key Responsibilities

The postdoctoral associate will be responsible for: protein production, purification, and analysis, including development and implementation of biochemical assaysinformatic and genome mining to identify, characterize, and understand the diverse biosynthetic pathways of bacterial sourcesprotein structure determination through X-ray crystallography and/or cryo-electron microscopy and single particle analysisData analysis, maintenance, and interpretation, including contributions on authoring publications and dissemination of research

Our benefits, where we prioritize your well-being and success to enhance every aspect of your life. Being a part of the University at Buffalo community.

The Research Foundation of SUNY is an EOE and welcomes all to apply including veterans and individuals with a disability.

Minimum Qualifications

• PhD in Biochemistry, Chemistry, or related field
• Background in protein biochemistry, enzymology, biophysical analysis, or structural biology
• Ability to analyze, publish, and present research data
• Self-motivation, ability to work both independently and collaboratively as a team
• Ability to manage time and organization on multiple projects

Preferred Qualifications

• Interest in natural product biosynthesis, including pathway reconstitution, genetic manipulation, small molecule isolation and characterization
• Expertise in enzymology, including assay development, LC-MS and HPLC analysis
• Experience with X-ray crystallographic analysis and protein structure determination or single particle cryo-electron microscopy structure determination and analysis
• Familiarity with computation tools for protein structure determination and analysis.

Salary Range

$55,000 - $65,000

Background Check

No

Contact Information

• Contact’s Name: Andrew Gulick
• Contact’s Pronouns:
• Contact’s Title: Professor
• Contact’s Email: [e-mail]
• Contact’s Phone: [phone]