Postdoc: Proteostasis in Hematopoiesis & Leukemia

Office of Intramural Training & Education; Bethesda (MD); On-site; USD 65,000 - 75,000; Full time

Job summary

The National Cancer Institute's Experimental Immunology Branch in Bethesda invites applications for a Postdoctoral Fellowship to investigate how proteostasis regulates hematopoietic stem and progenitor cell fate and leukemogenesis. The project leverages genomics, transcriptomics, and proteomics with state-of-the-art resources.

The successful candidate will perform CRISPR-based gene editing, utilize advanced genome/chromatin analysis, and collaborate across immunology, molecular biology, and

Qualifications

• Ph.D. in Immunology, Biochemistry, Molecular and Cell Biology, or related disciplines.
• Knowledge and experience in CRISPR-based gene editing is a plus.
• Experience with genomics, transcriptomics, and proteomics approaches is desired.

Responsibilities

• Elucidate transcriptional and epigenetic programs induced by proteotoxic stress in hematopoietic stem and progenitor cells.
• Use relevant human cells and novel animal models to perturb and track stress-induced signaling pathways in real-time.

Skills

Genomics

Proteomics

Immunology

Molecular biology

Stem cell biology

Education

Ph.D. in Immunology, Biochemistry, Molecular and Cell Biology, or related disciplines

Tools

CRISPR editing

ATAC-seq

ChIP-seq

Transcriptomics

Proteomics

Job description

The National Cancer Institute's Experimental Immunology Branch in Bethesda invites applications for a Postdoctoral Fellowship to investigate how proteostasis regulates hematopoietic stem and progenitor cell fate and leukemogenesis. The project leverages genomics, transcriptomics, and proteomics with state-of-the-art resources.

The successful candidate will perform CRISPR-based gene editing, utilize advanced genome/chromatin analysis, and collaborate across immunology, molecular biology, and