Postdoctoral Fellow: Immune Regulation of HSCs

Thecentermemphis; Memphis (TN); On-site; USD 61,625 - 83,375; Full time

Benefits offered by this job

Competitive compensation

Relocation assistance

Professional development opportunities

Job summary

St. Jude Children's Research Hospital invites applications for a postdoctoral researcher in the Yamashita Laboratory to explore how T cell–mediated immune surveillance regulates hematopoietic stem cells in the bone marrow.

The goal is to define mechanisms that influence clonal maintenance, graft-versus-leukemia activity, and hematologic disease outcomes. The successful candidate will work with state-of-the-art mouse models, flow cytometry, single-cell technologies, and collaborative teams to

Qualifications

• Strong background in immunology, hematology, stem cell biology, or related biomedical discipline.
• Experience with mouse handling and in vivo experimentation.
• Experience with flow cytometry and immune cell phenotyping.
• Experience with standard molecular and cellular biology techniques.
• Ability to design and execute experiments, analyze data, and interpret results independently.
• Excellent written and oral communication skills, including manuscript preparation.
• Strong organizational skills and the ability to work independently and in a team.
• Demonstrated commitment to scientific rigor, creativity, and problem-solving.

Responsibilities

• Conduct independent research on T cell–mediated regulation of HSCs and bone marrow immunity.
• Design and perform experiments using mouse models, flow cytometry, and molecular biology.
• Apply single-cell and other advanced technologies to study immune–stem cell interactions and disease mechanisms.
• Analyze data, present findings at meetings, and publish results in peer-reviewed journals.
• Collaborate with multidisciplinary teams and contribute to grant and manuscript preparation.
• Mentor students and trainees in a collaborative research environment.

Skills

Immunology

Flow cytometry

Mouse handling

Molecular biology

Independent research

Scientific communication

Team collaboration

Education

PhD/MD/MD-PhD in Immunology or related

Tools

Single-cell technologies

CRISPR-based genome editing

Translational immunology methods

Job description

St. Jude Children's Research Hospital invites applications for a postdoctoral researcher in the Yamashita Laboratory to explore how T cell–mediated immune surveillance regulates hematopoietic stem cells in the bone marrow.

The goal is to define mechanisms that influence clonal maintenance, graft-versus-leukemia activity, and hematologic disease outcomes. The successful candidate will work with state-of-the-art mouse models, flow cytometry, single-cell technologies, and collaborative teams to