Postdoc: Molecular Bacteriology—C. difficile Toxin

Kansas State University; Manhattan (KS); On-site; USD 52,000 - 65,000; Full time

Job summary

Kansas State University in Manhattan, KS, invites applications for an immediate Postdoctoral position in the Govind laboratory to study pathogenic mechanisms of Clostridioides difficile. The project focuses on toxin gene regulation, sporulation, and biofilm formation using RNA-Seq, genome sequencing, and proteomics.

The successful candidate will explore how c-di-GMP signaling affects virulence, relying on molecular biology, in vivo models, and bioinformatics.

Qualifications

• PhD required in Immunology, Microbiology, Cell Biology or related field.
• Experience with molecular techniques such as cloning, qRT-PCR, ELISA, protein expression and purification.
• ChIP-Seq, protein interaction studies, and in vivo models are advantageous; bioinformatic data analysis helpful.
• Strong communication skills and ability to work in a collaborative lab environment.

Responsibilities

• Investigate how c-di-GMP controls sporulation, toxin production, and biofilm formation in C. difficile.
• Characterize regulatory networks involved in virulence and sporulation.
• Apply omics approaches (RNA-Seq, genome sequencing, proteomics) to dissect gene regulation mechanisms.

Skills

Molecular techniques

Cloning

qRT-PCR

ELISA

Protein expression and purification

Education

PhD in Immunology, Microbiology, Cell Biology or related field

Tools

ChIP-Seq

RNA-Seq

Genomics

Proteomics

Job description

Kansas State University in Manhattan, KS, invites applications for an immediate Postdoctoral position in the Govind laboratory to study pathogenic mechanisms of Clostridioides difficile. The project focuses on toxin gene regulation, sporulation, and biofilm formation using RNA-Seq, genome sequencing, and proteomics.

The successful candidate will explore how c-di-GMP signaling affects virulence, relying on molecular biology, in vivo models, and bioinformatics.