Postdoctoral Position in Molecular Bacteriology

Kansas State University; Manhattan (KS); On-site; USD 52,000 - 65,000; Full time

Job summary

Kansas State University in Manhattan, KS, invites applications for an immediate Postdoctoral position in the Govind laboratory to study pathogenic mechanisms of Clostridioides difficile. The project focuses on toxin gene regulation, sporulation, and biofilm formation using RNA-Seq, genome sequencing, and proteomics.

The successful candidate will explore how c-di-GMP signaling affects virulence, relying on molecular biology, in vivo models, and bioinformatics.

Qualifications

• PhD required in Immunology, Microbiology, Cell Biology or related field.
• Experience with molecular techniques such as cloning, qRT-PCR, ELISA, protein expression and purification.
• ChIP-Seq, protein interaction studies, and in vivo models are advantageous; bioinformatic data analysis helpful.
• Strong communication skills and ability to work in a collaborative lab environment.

Responsibilities

• Investigate how c-di-GMP controls sporulation, toxin production, and biofilm formation in C. difficile.
• Characterize regulatory networks involved in virulence and sporulation.
• Apply omics approaches (RNA-Seq, genome sequencing, proteomics) to dissect gene regulation mechanisms.

Skills

Molecular techniques

Cloning

qRT-PCR

ELISA

Protein expression and purification

Education

PhD in Immunology, Microbiology, Cell Biology or related field

Tools

ChIP-Seq

RNA-Seq

Genomics

Proteomics

Job description

An immediate Postdoctoral position is available in the laboratory of Dr. Revathi Govind at Kansas State University, in Manhattan, Kansas. The mission of Dr. Govind's lab is to understand various pathogenic mechanisms of the anaerobic pathogen Clostridioides difficile. More specifically, we are interested in characterizing the interplay between the toxin gene regulatory networks and the sporulation pathways. We apply several omics technologies, such as RNA-Seq, genome sequencing, and proteomics, to dissect the gene regulatory networks and to characterize potential virulence and virulence-regulatory factors.

The successful candidate will investigate the mechanisms by which c-di-GMP controls sporulation, toxin production, and biofilm formation in C. difficile.

PROFESSIONAL EXPERIENCE/QUALIFICATIONS

Applicants interested in this position should hold a recent PhD degree in Immunology, Microbiology, Cell Biology, or a related area. Technical expertise in various molecular techniques, such as cloning, qRT-PCR, ELISA, protein expression and purification, is required. Experience with ChIP-Seq, protein-protein interaction studies, in vivo models is advantageous. Training in bioinformatic analysis of large datasets, such as RNA-Seq transcriptomics, genomics, and metabolomics, is valuable but not essential.