Portfolio Strategy Lead - Tech, Data & AI for Drug Discovery

6084-Janssen Research & Development, LLC Legal Entity; Brisbane (CA); Hybrid; USD 189,000 - 325,000; Full time

Benefits offered by this job

Consolidated retirement plan (pension)

401(k) savings plan

Long-term incentive program

Generous time-off benefits

Job summary

Johnson & Johnson Innovative Medicine seeks an exceptional Portfolio Strategy Lead to shape the future of drug discovery by uniting Tech, Data, and AI across TD, PSTS, JJT, and DDSAI. This leadership role requires unifying programs, aligning investments to priorities, and translating portfolio progress for senior leaders.

Remote work options may be considered case-by-case with approval. This position drives governance, execution discipline, and strategic storytelling to deliver bold outcomes for

Qualifications

• Bachelor’s degree in life sciences, data science, engineering, or a related field.
• Significant portfolio leadership, program leadership, strategy, or transformation experience in pharmaceutical R&D, biotech, healthcare, or a similarly complex innovation environment.
• Proven ability to lead across a matrixed organization, influencing senior stakeholders without direct authority.
• Strong understanding of one or more of the following: drug discovery, translational science, digital transformation, AI/data platforms, R&D technology, portfolio governance, or strategic investment planning.
• Demonstrated strength in executive communication, including translating complexity into clear decisions, narratives, and action plans for leadership teams.
• Experience managing cross-functional roadmaps, interdependencies, resource tradeoffs, and governance processes across multiple initiatives.
• Outstanding collaboration, judgment, and organizational leadership skills, with the ability to balance ambition with focus.

Responsibilities

• Lead the integrated Tech, Data & AI portfolio supporting TD and PSTS, connecting work across scientific, digital, and platform teams to deliver against DPDS’ strategic priorities.
• Provide Tech, Data, & AI portfolio oversight for AI-Native Drug Discovery, ensuring plans, milestones, dependencies, and investments are aligned across TD, PSTS, JJT, and DDSAI.
• Drive strategic alignment and prioritization across projects so resources remain focused on the most critical programs and are not diluted across lower-priority efforts.
• Connecting efforts to the Self Driving Labs initiative in TDS wherever possible and beneficial.
• Identify and unlock synergies across initiatives, especially where shared platforms, data pipelines, compute, automation, external partnerships, and operating models can accelerate impact.
• Partner closely with scientific, digital, and technology leaders to ensure project plans are integrated, realistic, and sequenced to support business and portfolio goals.
• Create transparency into portfolio investments and resource allocation, with clear reporting for senior leadership on where we are investing, what value is being unlocked, and where key risks or tradeoffs exist.
• Establish strong portfolio governance, including roadmap management, dependency tracking, prioritization forums, issue escalation, and executive-ready updates.
• Champion execution discipline and strategic storytelling, helping leaders communicate a compelling, consistent narrative around progress, investment needs, and long-term impact.

Skills

Advanced Analytics

Budget Management

Compliance Management

Critical Thinking

Data Analysis

Data Privacy Standards

Data Quality

Data Reporting

Data Savvy

Data Science

Data Visualization

Developing Others

Digital Fluency

Inclusive Leadership

Leadership

Program Management

Strategic Thinking

Succession Planning

Education

Bachelor's degree

Advanced degree

Job description

Johnson & Johnson Innovative Medicine seeks an exceptional Portfolio Strategy Lead to shape the future of drug discovery by uniting Tech, Data, and AI across TD, PSTS, JJT, and DDSAI. This leadership role requires unifying programs, aligning investments to priorities, and translating portfolio progress for senior leaders.

Remote work options may be considered case-by-case with approval. This position drives governance, execution discipline, and strategic storytelling to deliver bold outcomes for