Pediatrics & Neurology Gene Editing Scientist

Baylor College of Medicine; Houston (TX); On-site; USD 85,000 - 120,000; Full time

Job summary

Baylor College of Medicine in Houston, TX, seeks a Pediatrics - Neurology NRI (Instructor) to lead genome editing efforts across iPSCs, neural models, and organoids, advancing translational research in neurodevelopmental disorders.

The successful candidate will design CRISPR-based strategies, generate edited cell lines, and collaborate with genetics, bioinformatics, and electrophysiology teams to integrate multi-omics data and pushes the boundaries of human disease modeling.

Qualifications

• Ph.D. in Molecular Biology, Genetics, Neuroscience, Bioengineering, or related
• 3+ years of hands-on genome editing, particularly CRISPR-based approaches
• Demonstrated mammalian cell culture experience, including stem cells (iPSCs preferred)
• Experience with cloning, vector design, and delivery systems (viral and non-viral)
• Strong molecular biology skills (PCR, qPCR, NGS, Western blotting)
• Experience with clonal isolation and edited-line validation
• Ability to design experiments independently and troubleshoot protocols
• Strong organizational, analytical, and communication skills

Responsibilities

• Design, develop, and optimize genome editing strategies using CRISPR/Cas systems
• Generate and validate genetically modified cell lines, including iPSCs
• Perform clonal selection, screening, and molecular validation
• Collaborate with cross-functional teams to integrate multi-omics data
• Maintain detailed records and contribute to publications and grants
• Stay current with new genome editing technologies and implement them

Skills

Genome editing

Mammalian cell culture

PCR/qPCR

NGS

Communication

Experimental design

Education

Ph.D. in Molecular Biology/Genetics/Neuroscience/Bioengineering

Tools

CRISPR/Cas systems

Cloning/Vector design

Delivery systems (viral & non-viral)

iPSCs

Organoid/3D culture

Job description

Baylor College of Medicine in Houston, TX, seeks a Pediatrics - Neurology NRI (Instructor) to lead genome editing efforts across iPSCs, neural models, and organoids, advancing translational research in neurodevelopmental disorders.

The successful candidate will design CRISPR-based strategies, generate edited cell lines, and collaborate with genetics, bioinformatics, and electrophysiology teams to integrate multi-omics data and pushes the boundaries of human disease modeling.