Pathology Scientist: Imaging & Biomarker Discovery

Initial Therapeutics, Inc.; South San Francisco (CA); On-site; USD 120,000 - 190,000; Full time

Benefits offered by this job

Comprehensive employee benefits

Award-winning time-off plans

Flexible work models where possible

Job summary

Amgen is seeking a Scientist to join the Pathology Laboratory within the Translational Safety & Risk Sciences (TSRS) Department in South San Francisco, California. The Scientist will develop and apply tissue-based assays, including multiplex assays and digital image analysis, to support target expression studies, preclinical model development, pharmacodynamics, efficacy, and biomarker discovery.

Responsibilities include developing and validating histopathology assays, using imaging modalities,

Qualifications

• Doctorate or masters plus years of relevant research and industry experience.
• Experience with pathology-based methods, including IHC, multiplex IHC, ISH.
• Strong imaging and digital pathology exposure.

Responsibilities

• Develop, optimize, validate, and standardize histopathology assays on FFPE samples including IHC/ISH.
• Use imaging and digital pathology tools to analyze tissue-based data for biomarker development.
• Collaborate with pathologists and translational teams to support mechanism-of-action studies and safety assessments.
• Maintain documentation and communicate results through LIS, databases, and presentations.

Skills

Histopathology

IHC

ISH

Digital pathology

Image analysis

Team collaboration

Communication

Education

PhD in related field

Masters + 2+ years experience

Bachelors + 4 years experience

Tools

HALO

Visiopharm

Ventana

Leica Bond

IntelliPATH

Job description

Amgen is seeking a Scientist to join the Pathology Laboratory within the Translational Safety & Risk Sciences (TSRS) Department in South San Francisco, California. The Scientist will develop and apply tissue-based assays, including multiplex assays and digital image analysis, to support target expression studies, preclinical model development, pharmacodynamics, efficacy, and biomarker discovery.

Responsibilities include developing and validating histopathology assays, using imaging modalities,