Senior Scientist, mRNA Process Development

Eurofins; Boston, Northern (MA, KY); Hybrid; USD 55,000 - 63,000; Full time

Benefits offered by this job

Comprehensive medical, dental, and视on

401(k) with company match

Paid vacation and holidays

Yearly bonus & merit-based increases

Competitive hourly compensation

Job summary

Eurofins USA PSS Insourcing Solutions in Boston is seeking a Senior Scientist for mRNA process development. You will design, execute, and analyze experiments to develop GMP-compliant mRNA processes and support tech transfer toward manufacturing.

The role requires advanced degrees with bio/chemistry background, IVT experience, bioreactors, AKTA Avant, and Agilent 1260; collaboration with cross-functional teams, ensuring quality, safety, and documentation.

Qualifications

• B.S. degree in chemistry, chemical engineering, or biochemistry with 4+ years of relevant lab experience; M.S. with 2+ years; Ph.D. with 6 months+ experience.
• Experience supporting process development and manufacturing of protein, AAV, or mRNA therapeutics (preferably mRNA).
• Experience with process characterization and validation studies.
• Working knowledge of cGMP regulations and technology transfer.
• Experience with IVT processes and operating bioreactors/fermenters.
• Experience with downstream purification and analytical processes: TFF and chromatography including Akta Avant and Agilent 1260.
• Excellent communication, technical writing, and presentation skills.
• Strong attention to detail, organizational, work planning, problem solving, and critical thinking.
• Ability to work independently with little supervision.
• Authorization to work in the United States indefinitely without sponsorship.

Responsibilities

• Design, execute, and analyze experiments to develop and optimize mRNA process characterization techniques.
• Evaluate process performance and identify opportunities for productivity improvements.
• Support the transition of development-stage processes toward GMP-compliant manufacturing by establishing scalable, robust process parameters.
• Operate and troubleshoot bioreactors/fermenters.
• Develop, execute, optimize, and troubleshoot in vitro transcription (IVT) process development activities.
• Develop, execute, optimize, and troubleshoot chromatography systems including Cytiva AKTA Avant for purification and scale-up.
• Develop, execute, optimize, and troubleshoot chromatography systems including Agilent 1260 HPLC/UHPLC systems for nucleic acid analysis, impurity profiling, quantitation, and process characterization.
• Analyze and interpret data to support process optimization, troubleshooting, and technology transfer activities.
• Author and review GMP-relevant technical reports, protocols, batch records, and development summaries.
• Present findings to management and project teams.
• Uphold lab safety to the highest level of standards.

Skills

Communication skills

Technical writing

Presentation skills

Attention to detail

Independence

Education

Bachelor's degree in chemistry or biochemistry

Master's degree in chemistry or biochemistry

Ph.D. in chemistry/chemical engineering/biochemistry

Tools

AKTA Avant

Agilent 1260 UHPLC/HPLC

Bioreactors/fermenters

TFF

Job description

Eurofins USA PSS Insourcing Solutions in Boston is seeking a Senior Scientist for mRNA process development. You will design, execute, and analyze experiments to develop GMP-compliant mRNA processes and support tech transfer toward manufacturing.

The role requires advanced degrees with bio/chemistry background, IVT experience, bioreactors, AKTA Avant, and Agilent 1260; collaboration with cross-functional teams, ensuring quality, safety, and documentation.