Oligonucleotide Process Development Scientist II

Talentburst,-Inc

Cambridge (MA)

Sur place

USD 85 000 - 110 000

Plein temps

14 jours+

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Résumé du poste

Creative Solutions Services, LLC is seeking an Associate Scientist II to join the CMC - DS Process Development Group in Cambridge, MA. The 12-month contract role focuses on developing and scaling oligonucleotide synthesis processes to integrate Client chemistries into our platform.

The candidate will work with chemists and process scientists on method development, optimization, and in-process testing, ensuring high-quality documentation and adherence to safety standards in a fast-paced

Qualifications

  • BS in Chemistry or Chemical Engineering with 1-3 years of lab experience, preferably in an industrial setting.
  • Experience with record-keeping and laboratory documentation practices.
  • Ability to work as a team player in a dynamic environment with aggressive timelines.

Responsabilités

  • Support oligonucleotide synthesis method development, optimization and scale-up.
  • Support downstream processing method development.
  • Execution of in-process analytical testing.
  • Collaborate with researchers to develop robust processes for Client chemistries.

Connaissances

Analytical Skills
Lab Documentation
Team Collaboration

Formation

BS in Chemistry or Chemical Eng

Outils

HPLC
LC-MS
Phosphoramidite Chemistry

Description du poste

Associate Scientist II
Cambridge,MA
12 months contract

Job Summary

The successful candidate will be a part of the CMC - DS Process Development Group, responsible for the process development to incorporate Client chemistries into our manufacturing platform.

Summary of Key Responsibilities:
- Support oligonucleotide synthesis method development, optimization and scale-up
- Support downstream processing method development
- Execution of in-process analytical testing
- Working with research and process scientists to develop robust processes for Client chemistries

Skills:
- Basic understanding of analytical techniques (pH, osmolality, conductivity measurement, HPLC, LC-MS etc.). Related hands-on experience is preferred. Knowledge of oligonucleotide manufacture process including phosphoramidite chemistry, chromatography, ultrafiltration etc. is a plus.
- Experience in record-keeping and excellent laboratory documentation practice are required. Strong commitment to high laboratory and scientific standard; ability to maintain a safe, clean, and orderly laboratory work environment; assist in routine lab and equipment maintenance.
- Good communication skills are a must for this position. The successful candidate must be a responsible and proactive individual who is able to work as a team player in a highly dynamic environment with aggressive timelines.

Education:
- BS in Chemistry or Chemical Engineering with 1-3 years of lab experience, preferably in an industrial setting.

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