Scientist 1, Chemistry Development - Entry Level

MillenniumSoft Inc; Baltimore (MD); On-site; USD 28,000 - 41,000; Full time

Job summary

MillenniumSoft Inc. in Sparks, MD seeks an entry-level Scientist I for a 12-month contract (W-2). The role focuses on synthesizing and purifying oligonucleotides using automated systems and LC/HPLC setups within a GMP/GLP environment.

Typical hours are Mon–Fri, 8:30am–5pm, with a 40-hour week. Candidate should hold a Bachelor's in Biochemistry/Chemistry/Molecular Biology and have up to 1 year of relevant experience.

Qualifications

• Bachelor’s degree in Biochemistry, Chemistry, Molecular Biology or related discipline.
• Prefer a minimum of 1 year of industrial or academic experience in the synthesis and/or purification of oligonucleotides.
• Familiarity with GMP/GLP laboratory guidelines.

Responsibilities

• Synthesize and purify oligonucleotides per established protocols.
• Prepare buffers for oligonucleotide and conjugation processes.
• Contribute to oligonucleotide process optimization projects.
• Provide documentation and validation support for synthesis/purification changes.
• Perform GMP/GLP-compliant laboratory tasks under supervision.

Skills

Oligonucleotide synthesis

HPLC

GMP/GLP awareness

Education

Bachelor’s degree in Biochemistry/Chemistry/Molecular Biology

Tools

Oligonucleotide synthesizer

LC systems

Job description

Level of Experience : Entry Level

Employment Type : Contract on W2 (Need US Citizens or GC Holders or GC EAD or OPT or EAD or CPT)
Work days/hours: M - F 8:30am -- 5pm

Position : Scientist I
Location : Sparks, MD
Duration : 12 Months
Total Hours/week : 40.00
rate:$20-30/hr
1st Shift
Client : Medical Devices Company
Level of Experience : Entry Level
Employment Type : Contract on W2 (Need US Citizens or GC Holders or GC EAD or OPT or EAD or CPT)
Work days/hours: M - F 8:30am -- 5pm
Job Description

• Works within a team to provide synthetic oligonucleotides through the use of automated oligonucleotide synthesizers and Liquid Chromatography systems which support the development of automated assays using nucleic acid isolation and real-time amplification/detection technology within the Molecular Diagnostic plants.

Duties And Responsibilities

• Follows established protocols for the synthesis and purification of oligonucleotides used in manufacturing and R&D.
• Follows established protocols for the preparation of buffers used in the oligonucleotide and conjugation processes.
• Follows established protocols for protein conjugation procedures.
• Contributes to the completion of goals associated with specific oligonucleotide process optimization projects.
• Contributes to developing solutions and providing recommendations as to the appropriate course of action to technical problems associated with the preparation of synthetic oligonucleotides.
• Provides documentation and validation support in execution of synthesis and/or purification process changes.
• Performs laboratory work and documentation in accordance with GMP, GLP and company guidelines.
• Perform tasks under general supervision.

Qualifications

Knowledge and skills:

• Basic understanding in the use of the liquid chromatography manual or automated systems.
• Basic understanding of chromatography theory and hands-on experience with HPLC
• (High Performance Liquid Chromatography).
• Excellent verbal and written communication skills are necessary together with the
• ability to interact effectively in team and cross-functional environments.
• Understanding of the GMP and GLP laboratory guidelines.
• Optional experience includes the use of a DNA (oligonucleotide) and/or Peptide
• synthesizer and having an understanding of the oligonucleotide synthesis chemistry.
• Understanding of Lean manufacturing tools highly beneficial.

Education And Experience

• Minimum of a Bachelor’s Degree in Biochemistry, Chemistry, Molecular Biology or related discipline.
• Prefer a minimum of 1 year of industrial or academic experience in the synthesis and/or purification of oligonucleotides.