Night-Shift Maintenance Manager, Drug Substance

Amgen SA; Juncos (PR); On-site; USD 120,000 - 150,000; Full time

Benefits offered by this job

Retirement and Savings Plan

Health, dental & vision coverage

Life & disability insurance

Discretionary annual bonus program

Stock-based long-term incentives

Paid time off and site shutdowns

Flexible work models where possible

Job summary

Amgen is hiring a Manager Maintenance – AML6 Drug Substance for a 12‑hour night shift. You’ll lead maintenance activities to align with production schedules, manage a multi skilled team, and ensure compliance. The role emphasizes reliability, planning, and safety across the AML6 plant.

You will drive continuous improvement, oversee budgeting, and collaborate with manufacturing, support and external partners. Fluency in English and Spanish is preferred, with strong leadership and technical skills.

Qualifications

• Doctorate or Master’s with experience in Maintenance/Engineering leadership.
• Minimum years of maintenance/engineering support experience as applicable to degree level.
• Managerial experience directly managing people or leading teams/projects.
• Experience with regulated manufacturing and cGMP compliance preferred.

Responsibilities

• Lead maintenance vision, strategy and goals for a best-in-class org.
• Manage Instrument/maintenance tech team—training, performance, workload.
• Oversee corrective/preventive maintenance and calibration programs.
• Coordinate maintenance planning with other functions to minimize downtime.
• Document activities in CMMS, analyze trends, implement actions.
• Develop and maintain procedures, training and job plans.
• Ensure safe operations with health, safety and housekeeping practices.
• Support Change Controls and CAPA; assist validation and audits.
• Lead continuous improvement via Lean/Six Sigma methodologies.
• Manage maintenance budget and during plant slowdowns/shutdowns.

Skills

People leadership

Maintenance management

Safety programs

English & Spanish communication

Education

Doctorate degree

Master’s degree + 3 years experience

Bachelor’s degree + 5 years experience

Associate’s degree + 10 years experience

High school diploma / GED + 12 years experience

Tools

CMMS

MS Office

Job description

Amgen is hiring a Manager Maintenance – AML6 Drug Substance for a 12‑hour night shift. You’ll lead maintenance activities to align with production schedules, manage a multi skilled team, and ensure compliance. The role emphasizes reliability, planning, and safety across the AML6 plant.

You will drive continuous improvement, oversee budgeting, and collaborate with manufacturing, support and external partners. Fluency in English and Spanish is preferred, with strong leadership and technical skills.