Manager Maintenance – AML6 Drug Substance (12 hrs./Night Shift)

1044 Amgen Manufacturing Limited LLC; Juncos (PR); On-site; USD 100,000 - 150,000; Full time

Benefits offered by this job

Comprehensive employee benefits

Discretionary annual bonus

Stock-based long-term incentives

Generous time-off / site shutdown

Job summary

Amgen Inc. seeks a Manager Maintenance – AML6 Drug Substance to lead a multi-skilled maintenance team in a 12-hour night shift. You will drive reliability, manage maintenance planning, and oversee calibration programs in a regulated biotech plant.

This role requires strong leadership, strategic direction, and collaboration with Manufacturing and Support areas. You will develop procedures, train staff, and ensure safety, compliance, and continuous improvement using Lean/Six Sigma methods.

Qualifications

• In-depth maintenance and engineering support experience, including leadership roles.
• Experience managing people and projects within a regulated manufacturing environment.
• Knowledge of CMMS, reliability, and preventive maintenance practices.
• Strong communication skills in English and Spanish and ability to work across levels.

Responsibilities

• Lead and develop a team of Instrument and/or Maintenance Technicians.
• Oversee corrective, preventive maintenance and calibration programs.
• Drive maintenance planning and scheduling with cross-functional partners.
• Manage Change Controls and CAPA; support validation and audits.

Skills

Maintenance leadership

Team management

Lean Six Sigma

CMMS

Safety compliance

English and Spanish

Education

Doctorate or Master’s in Maintenance/Engineering

Bachelor’s in Maintenance/Engineering

Associate’s in Maintenance/Engineering

High school diploma/GED with experience

Tools

CMMS systems

Microsoft Office Suite

Bioreactors knowledge

Chromatography

Centrifugation

Job description

Career Category Maintenance Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat heart disease, obesity and obesity‑related conditions, rare diseases, inflammatory conditions and cancer. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award‑winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Manager Maintenance – AML6 Drug Substance (12 hrs./Night Shift)

What you will do

In this vital role you will be responsible for the leadership and execution of maintenance activities in accordance to the production schedule and compliance requirements. You will assure process reliability by providing effective management of the Maintenance Program and associated resources. Converts the organization’s asset management strategy into workplace activities, provides technical expertise, strategic direction and management to a multi skilled maintenance work force from the AML6 Drug Substance Manufacturing Plant in a 12‑hour non‑standard shift operation.

• Support the development and execution of the Maintenance vision, strategy, and goals to advance a best‑in‑class Maintenance Organization.
• Lead, develop, and manage a team of Instrument and/or Maintenance Technicians, including workload prioritization, training, technical development, performance management, and quality of work.
• Lead corrective, preventive maintenance, and calibration programs to ensure timely, effective repairs and execution of planned maintenance activities in accordance with established targets, compliance requirements, and available maintenance windows.
• Drive maintenance planning and scheduling in partnership with Maintenance, Manufacturing, and Support areas to minimize operational impact and continuously improve the planning and scheduling process.
• Use the CMMS to document maintenance activities, maintain equipment and spare‑parts records, prepare reports, analyze performance trends, and recommend or implement corrective actions.
• Develop, review, and maintain procedures, training materials, and job plans; provide technical guidance in accordance with applicable standards, codes, and best practices.
• Ensure a safe work environment by implementing safety programs and maintaining appropriate housekeeping practices within maintenance shops and operating areas.
• Manage Change Controls and CAPA requirements; support validation activities, deviation investigations, compliance audits, and Quality events.
• Lead maintenance continuous improvement initiatives using Lean/Six Sigma methodologies to improve reliability, efficiency, and maintenance execution.
• Support management of the maintenance section budget and expenses.
• Lead maintenance logistics and execution during planned plant slowdowns and shutdowns.
• Build and maintain effective working relationships with internal and external customers, contractors, and suppliers.
• Support night and 12hrs non‑standard shifts, including extended hours, as per business needs.

What we expect of you

We are all different! Yet, we all use our unique contributions to serve patients. The Mgr Maintenance professional we seek is a collaborative people leader with these qualifications.

Basic Qualifications

• Doctorate degree or Master’s degree and 3 years of Maintenance and/or Engineering support experience
• Bachelor’s degree and 5 years of Maintenance and/or Engineering support experienceAssociate’s degree and 10 years of Maintenance and/or Engineering support experience
• High school diploma / GED and 12 years of Maintenance and/or Engineering support experience
• In addition to meeting at least one of the above requirements, you must have previous managerial experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation of resources.
• Managerial experience may run concurrently with the required technical experience referenced above.

Preferred Qualifications

• Bachelor’s or master’s degree in Life Sciences and/or Engineering
• Hands‑on experience providing troubleshooting support
• Knowledge of biotechnology equipment and processes used in Drug Substance operations, including bioreactors, chromatography, and centrifugation
• Demonstrated initiative to help the team take a proactive rather than reactive approach
• Progressive technical and managerial experience in Maintenance and/or Engineering within a regulated manufacturing environment
• Strong knowledge of industrial equipment and facilities, applicable compliance regulations, maintenance programs, reliability practices, and predictive/preventive maintenance
• Experience with reliability practices, and familiarity with validation process and cGMP documentation
• Demonstrated leadership, team‑building, staff relations, coaching, mentoring, and employee counseling skills
• Experience operating with a high degree of organizational skill, urgency, negotiation, collaboration, and the ability to prioritize multiple tasks in a fast‑paced, changing, 24/7 operation
• Lean/Six Sigma experience and a demonstrated continuous improvement mindset; Green Belt, Black Belt, or other Continuous Improvement certifications are preferred
• Strong written and verbal communication skills in English and Spanish, including the ability to prepare high‑quality reports and deliver presentations to multiple organizational levels
• Advanced computer skills, including proficiency in the Microsoft Office Suite and working knowledge of CMMS systems
• Availability to support a non‑standard shift organization, as per business needs

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well‑being.

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental & vision coverage, and life & disability insurance.
• A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan.
• Stock‑based long‑term incentives.
• Award‑winning time-off plans and an annual site shutdown Flexible work models where possible.

Sponsorship

Sponsorship for this role is not guaranteed.

Equal Opportunity

Amgen is an Equal Opportunity employer. We make all employment decisions without regard to race, color, religion, sex or any other characteristic protected by applicable law. We provide reasonable accommodations to applicants and employees with disabilities, consistent with legal requirements. Please contact us to request accommodation.

Company Overview

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

For more information, visit www.amgen.com and follow us on www.twitter.com/amgen