Night Shift Manufacturing Leader - Flexible Work Models

BioSpace; New Albany (OH); On-site; USD 150,000 - 210,000; Full time

Benefits offered by this job

Total Rewards Plan

Discretionary annual bonus

Stock-based incentives

Generous time-off plans

Flexible work model

Job summary

Amgen is seeking a Night Senior Manager Manufacturing Night Operations Performance & Integration to lead the night-shift operating system, ensuring safe, compliant, high-performing production across the shift. You will collaborate with Engineering, QA, Automation, and Maintenance to optimize performance and reliability.

The role requires advanced GMP manufacturing leadership with a strong track record in lean practices, escalation, and cross-functional teamwork.

Qualifications

• Doctorate degree with 2 years in GMP manufacturing, process development, or related six sigma lean operational excellence.
• Masters degree with 6 years in GMP manufacturing, process development, or related six sigma lean operational excellence.
• Bachelor's degree with 8 years in GMP manufacturing, process development, or related six sigma lean operational excellence.
• Associate degree with 10 years in GMP manufacturing, process development, or related six sigma lean operational excellence.
• High school diploma or GED with 12 years in GMP manufacturing, process development, or related six sigma lean operational excellence.
• Minimum of 2 years experience directly managing people and/or leadership experience leading teams, projects, or resources.

Responsibilities

• Serve as the senior Manufacturing integration point across night-shift operations during significant operational events.
• Establish and sustain the night-shift Tier structure, operating cadence, escalation model, and performance-management routines.
• Coordinate Manufacturing, QA, Engineering, Automation, Maintenance, Supply Chain/Warehouse, and other site resources to maintain safe, compliant, and reliable operations.
• Drive escalation of significant resource constraints, technical barriers, competing priorities, or unresolved operational issues to appropriate site or functional leadership.
• Monitor overall night-shift Manufacturing performance across production lines, including downtime, OEE, schedule attainment, recurring interruptions, escalation effectiveness, and chronic losses.
• Partner with the daytime Manufacturing Senior Manager, Continuous Improvement Senior Manager and MFG process Support Senior Manager to identify, prioritize, and execute improvement opportunities across off-shift, including 5S, visual management, standard work, workplace organization, waste reduction, flow improvement, and training operating discipline.
• Provide coaching and situational leadership to Front Line Managers during complex operational events

Skills

Leadership

GMP knowledge

Lean principles

Cross-functional collaboration

Education

Doctorate degree

Master's degree

Bachelor's degree

Associate degree

High school diploma/GED

Job description

Amgen is seeking a Night Senior Manager Manufacturing Night Operations Performance & Integration to lead the night-shift operating system, ensuring safe, compliant, high-performing production across the shift. You will collaborate with Engineering, QA, Automation, and Maintenance to optimize performance and reliability.

The role requires advanced GMP manufacturing leadership with a strong track record in lean practices, escalation, and cross-functional teamwork.