Neuroscience Research Assistant - iPSC & Cell Biology

massgeneralbrigham; Boston (MA); On-site; USD 29,000 - 40,000; Full time

Job summary

Mass General Brigham in Boston is seeking a hands-on Laboratory Specialist to support iPSC-derived neuron projects under supervision. You will perform routine experiments, manage data, and contribute to assay development for viability and toxicity testing, with emphasis on cell culture, molecular biology, and imaging workflows.

The role requires strong organization, meticulous lab records, and the ability to work collaboratively in a fast-paced translational research environment.

Qualifications

• Bachelor's degree in science required or equivalent work experience.
• 0-1 year relevant coursework preferred for new grads.
• Excellent cell culture practices with sterile technique.
• Good understanding of molecular biology methods (cloning, Western blot, qPCR).
• Basic computer literacy and data management skills.
• Strong communication and organizational abilities.

Responsibilities

• Maintain, passage, catalogue, and culture iPSC cells.
• Differentiate iPSCs to neurons and age cultures.
• Operate Attune flow cytometer and manage reagents.
• Schedule longitudinal imaging with Incucyte and Nikon Biostation.
• Maintain HEK293 cells and generate stable lines.
• Assist with molecular cloning and related prep work.
• Analyze data from western blot, microscopy, and flow cytometry.
• Maintain lab notebooks and write SOPs.
• Report to supervisor daily and to PI weekly.
• Collaborate with team to troubleshoot experiments.
• Share lab duties with technicians.
• Data collection, management, and reporting.
• Study cohort management and outreach communications.
• Provide support for epidemiological studies.

Skills

Cell culture

Molecular cloning

Flow cytometry

Western blot

Data management

SOPs documentation

Communication skills

Organization

Education

Bachelor's degree in Science

Tools

Attune flow cytometer

Incucyte microscope

Nikon Biostation

Job description

Mass General Brigham in Boston is seeking a hands-on Laboratory Specialist to support iPSC-derived neuron projects under supervision. You will perform routine experiments, manage data, and contribute to assay development for viability and toxicity testing, with emphasis on cell culture, molecular biology, and imaging workflows.

The role requires strong organization, meticulous lab records, and the ability to work collaboratively in a fast-paced translational research environment.