MRD NGS Scientist I

Veracyte; South San Francisco (CA); On-site; USD 130,000 - 140,000; Full time

Job summary

Veracyte in South San Francisco is seeking a Scientist I to support the development of next‑generation MRD assays from concept through clinical laboratory implementation. This laboratory-based role executes experiments, analyzes data, and helps optimize assay development, workflow automation, and validation readiness in a collaborative, fast‑paced product development environment.

The ideal candidate has hands‑on molecular biology and NGS experience, and a passion for developing diagnostic

Qualifications

• Ph.D. in Molecular Biology, Genetics, Biochemistry, Cancer Biology, or related field
• Minimum of 3 years of relevant industry and/or postdoctoral experience in molecular diagnostics, biotechnology, genomics, or a related field
• Hands-on experience with NGS-based molecular biology techniques including library preparation and supporting analytical methods
• Strong understanding of molecular genomic technologies, including DNA- and/or RNA-based assays
• Experience with experimental design, execution, data analysis, and interpretation
• Familiarity with statistical analysis and data visualization tools such as JMP, R, Python, or equivalent
• Experience working with clinical sample types, including blood, plasma, tissue, or FFPE specimens, is preferred
• Exposure to regulated product development environments and quality systems (CAP/CLIA, NYSDOH, design control) is desirable
• Experience with oncology, liquid biopsy, ctDNA, or MRD technologies is a plus

Responsibilities

• Support development, optimization, verification, and transfer of NGS-based MRD assays under the guidance of senior technical team members from early feasibility through clinical laboratory implementation
• Execute feasibility, characterization, optimization, and pre-validation studies to support assay and workflow development
• Procure, qualify, prepare, and characterize clinical and contrived samples for assay development and validation studies
• Contribute to experimental design, study planning, execution, analysis, and interpretation in collaboration with senior scientists and technical leads
• Generate high-quality laboratory data and maintain accurate documentation in accordance with design control and quality system requirements
• Contribute to SOPs, protocols, reports, and other development documentation supporting product development activities
• Support development and optimization of automated high-throughput laboratory workflows
• Participate in assay troubleshooting, root-cause investigations, and implementation of technical improvements
• Collaborate with cross-functional teams including Bioinformatics, Data Science, Operations, Clinical Laboratory, Automation, Quality, Regulatory, and Software/LIMS to advance product development objectives
• Support technology transfer, assay implementation, and validation activities within the clinical laboratory environment

Skills

Molecular biology

NGS workflows

Data analysis

Collaboration

qPCR

Education

Ph.D. in Molecular Biology, Genetics, Biochemistry, Cancer Biology, or related field

Tools

Tapestation

Fragment analysis

qPCR

JMP / R / Python

Job description

Veracyte in South San Francisco is seeking a Scientist I to support the development of next‑generation MRD assays from concept through clinical laboratory implementation. This laboratory-based role executes experiments, analyzes data, and helps optimize assay development, workflow automation, and validation readiness in a collaborative, fast‑paced product development environment.

The ideal candidate has hands‑on molecular biology and NGS experience, and a passion for developing diagnostic