Mouse Model Biologist – Immunology & Genotyping

Guidehouse; Bethesda (MD); On-site; USD 74,000 - 124,000; Full time

Benefits offered by this job

Medical, Rx, Dental & Vision Insurance

401(k) Retirement Plan

Paid Holidays

Job summary

Guidehouse in Bethesda, MD is seeking a Scientist to support and manage mouse colonies and disease models for NIH collaborations. This full-time role requires hands-on experimental work, collaboration across multidisciplinary teams, and leadership of independent projects aligned with NIH labs' goals.

The candidate will perform genotyping, breeding oversight, and prepare animals for experiments, with strong immunology and molecular biology techniques. A federal/public trust clearance is preferred.

Qualifications

• At least 3 years of research experience in molecular biology, cell biology, immunology, or related biomedical research OR a Master’s degree with 1+ year of relevant experience.
• Deep experience in managing and maintaining large mouse colonies, genotyping, and mouse models; experience with cell culture, PCR/qPCR/ddPCR, flow cytometry or related techniques.
• Ability to work independently and collaborate across multidisciplinary teams; ability to obtain and maintain federal/public trust.

Responsibilities

• Support and manage the laboratory’s mouse colonies and mouse models for all lab members.
• Assist with experimental work and lead independent research projects aligned with NIH goals.
• Maintain and manage mouse colonies and animal work while supporting team members during experiments.
• Perform genotyping of the mouse colony used by the laboratory.
• Set up and oversee maintenance breeding of all mouse strains.
• Generate and maintain new mouse lines through crossbreeding.
• Prepare animals for experimentation and related procedures.
• Assist with animal studies including blood collection and tissue processing.
• Perform immunology and molecular biology techniques with animal and human cells/tissues.
• Keep the Animal Protocol up to date and develop new skills relevant to models.

Skills

Research experience

Independent work

Collaboration across teams

Documentation and data analysis

Education

B.A. or B.S. in scientific discipline

Master’s degree in scientific discipline

Job description

Guidehouse in Bethesda, MD is seeking a Scientist to support and manage mouse colonies and disease models for NIH collaborations. This full-time role requires hands-on experimental work, collaboration across multidisciplinary teams, and leadership of independent projects aligned with NIH labs' goals.

The candidate will perform genotyping, breeding oversight, and prepare animals for experiments, with strong immunology and molecular biology techniques. A federal/public trust clearance is preferred.