Research Scientist

Dovel Technologies, Inc; Bethesda (MD); On-site; USD 98,000 - 163,000; Full time

Benefits offered by this job

Medical

Dental & Vision Insurance

401(k) Retirement Plan

Tuition Reimbursement

Personal Development

Employee Referral Program

Job summary

Guidehouse is seeking a Research Scientist to support the National Heart, Lung, and Blood Institute in Bethesda, MD. The role includes immunology, molecular biology, and sequencing work across human and animal samples, with responsibilities spanning from bench to manuscript preparation.

The candidate will engage with multiple core facilities, present at meetings, and assist with regulatory documents. A PhD or MD-equivalent and 6+ years of experience are required for a fast-paced environment.

Qualifications

• Ph.D. or M.D. or other appropriate doctoral degree in science, medicine, or related field.
• Minimum of SIX (6) years of research experience in science, medicine, or related fields.
• Extensive experience in molecular biology, biochemistry, and immunology research, including experience in immune cell development and function.
• Experience generating knockout mice, conditional knockout mice, and extensive experience working with mice/mouse models.
• Extensive experience related to next generation sequencing methods and analyses (e.g., RNA-seq, scRNA-seq, ChIP-seq, ATAC-seq, Hi-C, HiChIP, PCA, UMAP, tSNE).
• Experience with advanced molecular biology techniques (e.g., ChIP, co-IP, advanced cloning techniques, western blotting, Northern blotting, Southern blotting, Q-PCR).
• Experience with flow cytometry, immunohistochemistry, and metabolomics.
• Extensive experience in cell culture and/or extensive knowledge of cell biology.
• Ability to manage and coordinate high-priority short- and long-term projects and studies in a fast-paced environment.

Responsibilities

• Perform immunology and molecular biology techniques with animal and human cells/tissues.
• Perform a range of biochemical assays, immunoprecipitations, PAGE and western blotting.
• Perform next generation sequencing techniques for transcriptomics and epigenetic analyses.
• Perform immunofluorescence staining and functional analyses of tissue samples.
• Work with sequencing, mass spectrometry, flow cytometry, and other cores as needed.
• Maintain mouse lines (breeding, genotyping).
• Present research at international and national research meetings.
• Assist the Lab Chief in creating/preparing required documents (CRADAs, MTAs, Patent Applications, Animal Protocols, BSC review).
• Review, edit, and write drafts of papers, posters and manuscripts.
• Act as scientific consultant and collaborator for IRTA fellows and Visiting Fellows.

Skills

Molecular biology

Immunology

Next-gen sequencing

Mouse models

Biochemical assays

Flow cytometry

Cell culture

Data presentation

Education

Ph.D. or M.D. or related doctoral degree

Tools

Flow cytometry

Mass spectrometry

Western blotting

Job description

Job Family: Scientist Travel Required: Up to 10% Clearance Required: Ability to Obtain Public Trust

What You Will Do:

We are currently searching for a Research Scientist.

This role will independently provide support services to satisfy the overall operational objectives of the National Heart, Lung, and Blood Institute.

The primary objective is to provide services and deliverables through performance of support services.

This is a full-time opportunity located in Bethesda, MD.

Perform a wide array of immunology and molecular biological techniques with animal and human cells/tissues.

Perform a variety of biochemical assays, immuno-precipitations, polyacrylamide gel electrophoresis and western blotting.

Perform a range of next generation sequencing techniques, including for transcriptomics and epigenetic analyses.

Perform immunofluorescence staining and functional analyses of tissue samples.

Work with the sequencing, mass spectrometry, flow cytometry, and other cores as needed.

Maintain mouse lines (breeding, genotyping).

Present research at international and national research meetings.

Conduct and help direct independent research projects of high priority for the laboratory.

Assist the Lab Chief in the creating/preparing documents required by the Lab Chief’s scientific activities (e.g., CRADAs, Material Transfer Agreements, Patent Applications, Animal Protocols, BSC review).

Review, edit, and write drafts of papers, posters and manuscripts produced within the laboratory for consistency of the research agenda, adherence to any applicable scientific policies, and clarity of presentation of data and other scientific information.

Act as a scientific consultant, technical expert, and collaborator for IRTA fellows, Visiting Fellows, and others in the lab as needed.

What You Will Need:

• Ph.D. or M.D. or other appropriate doctoral degree in science, medicine, or related field
• Minimum of SIX (6) years of research experience in science, medicine, or related fields.
• Extensive experience in molecular biology, biochemistry, and immunology research, including experience in immune cell development and function.
• Experience generating knockout mice, conditional knockout mice, and extensive experience working with mice/mouse models.
• Extensive experience related to next generation sequencing methods and analyses (e.g., RNA-seq, scRNA-seq, ChIP-seq, ATAC-seq, Hi-C, HiChIP, PCA, UMAP, tSNE).
• Experience with advanced molecular biology techniques (e.g., ChIP, co-IP, advanced cloning techniques, western blotting, Northern blotting, Southern blotting, Q-PCR).
• Experience with flow cytometry, immunohistochemistry, and metabolomics.
• Extensive experience in cell culture and/or extensive knowledge of cell biology.
• Ability to manage and coordinate high-priority short- and long-term projects and studies in a fast-paced environment.

What Would Be Nice To Have:

• Previous experience with NIH preferred.
• Proficient in Microsoft Office and PowerPoint

The annual salary range for this position is $98,000.00-$163,000.00.

What We Offer:

• Medical
• Rx
• Dental & Vision Insurance
• Personal and Family Sick Time & Company Paid Holidays
• Parental Leave
• 401(k) Retirement Plan
• Group Term Life and Travel Assistance
• Voluntary Life and AD&D Insurance
• Health Savings Account
• Health Care & Dependent Care
• Flexible Spending Accounts
• Transit and Parking Commuter Benefits
• Short-Term & Long-Term Disability
• Tuition Reimbursement
• Personal Development
• Certifications & Learning Opportunities
• Employee Referral Program
• Corporate Sponsored Events & Community Outreach
• Care.com annual membership
• Employee Assistance Program
• Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)

About Guidehouse

Guidehouse is an Equal Opportunity Employer–Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation. Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.

If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at [e-mail]. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation. All communication regarding recruitment for a Guidehouse position will be sent from Guidehouse email domains including @guidehouse.com or [e-mail]. Correspondence received by an applicant from any other domain should be considered unauthorized and will not be honored by Guidehouse.

Guidehouse is a global AI-led professional services firm delivering advisory, technology, and managed services to the commercial and government sectors. With an integrated business technology approach, Guidehouse drives efficiency and resilience in the healthcare, financial services, energy, infrastructure, and national security markets. Built to help clients across industries outwit complexity, the firm brings together approximately 18,000 professionals to achieve lasting impact and shape a meaningful future. guidehouse.com