Biologist

Guidehouse; Bethesda (MD); On-site; USD 74,000 - 124,000; Full time

Benefits offered by this job

Medical, Rx, Dental & Vision Insurance

401(k) Retirement Plan

Paid Holidays

Job summary

Guidehouse in Bethesda, MD is seeking a Scientist to support and manage mouse colonies and disease models for NIH collaborations. This full-time role requires hands-on experimental work, collaboration across multidisciplinary teams, and leadership of independent projects aligned with NIH labs' goals.

The candidate will perform genotyping, breeding oversight, and prepare animals for experiments, with strong immunology and molecular biology techniques. A federal/public trust clearance is preferred.

Qualifications

• At least 3 years of research experience in molecular biology, cell biology, immunology, or related biomedical research OR a Master’s degree with 1+ year of relevant experience.
• Deep experience in managing and maintaining large mouse colonies, genotyping, and mouse models; experience with cell culture, PCR/qPCR/ddPCR, flow cytometry or related techniques.
• Ability to work independently and collaborate across multidisciplinary teams; ability to obtain and maintain federal/public trust.

Responsibilities

• Support and manage the laboratory’s mouse colonies and mouse models for all lab members.
• Assist with experimental work and lead independent research projects aligned with NIH goals.
• Maintain and manage mouse colonies and animal work while supporting team members during experiments.
• Perform genotyping of the mouse colony used by the laboratory.
• Set up and oversee maintenance breeding of all mouse strains.
• Generate and maintain new mouse lines through crossbreeding.
• Prepare animals for experimentation and related procedures.
• Assist with animal studies including blood collection and tissue processing.
• Perform immunology and molecular biology techniques with animal and human cells/tissues.
• Keep the Animal Protocol up to date and develop new skills relevant to models.

Skills

Research experience

Independent work

Collaboration across teams

Documentation and data analysis

Education

B.A. or B.S. in scientific discipline

Master’s degree in scientific discipline

Job description

What You Will Do

We are currently searching for specialized scientific services to support and manage the laboratory's mouse colonies and mouse models of disease for the NIH. This is a full-time role in Bethesda, MD.

• Support and manage the laboratory's mouse colonies and mouse models of disease for all lab members.
• Assist with experimental work and lead independent research projects aligned with the NIH labs research goals.
• Maintain and manage the laboratory's mouse colonies and animal work while supporting team members (and sometimes collaborators) during animal experiments in ongoing projects.
• Perform the genotyping of the entire mouse colony used by the laboratory.
• Set up and oversee maintenance breeding of all mouse strains.
• Generate and maintain needed new mouse lines through crossbreeding.
• Prepare animals for experimentation, including generation of bone-marrow chimeras, infection with LCMV or IAV, etc.
• Assist with animal studies, including blood collection, tissue processing, pathology support, and preclinical analysis.
• Perform a wide array of immunology and molecular biological techniques with animal and human cells/tissues.
• Assist in keeping the Animal Protocol up to date.
• Acquire new skills related to animal models to help the laboratory perform cutting‑edge disease‑relevant work.
• Support collaborations with investigators, staff scientists, and partner laboratories.
• Contribute to projects and publications.
• Prepare PowerPoint slides and other items valuable for presentation of laboratory accomplishments.
• Develop work products and documents related to analyzing, evaluating, and interpreting scientific data to prepare papers for publication in peer‑reviewed journals and, when indicated, present findings at seminars and/or scientific meetings.
• Maintain a lab-accessible database of the laboratory's mouse colonies and ongoing animal experiments.

Job Family

Scientist

Travel Required

None

Clearance Required

Ability to Obtain Public Trust

What You Will Need

• B.A. or B.S. degree in a scientific discipline and at least THREE (3) years of research experience in molecular biology, cell biology, immunology, or related biomedical research OR a Master’s degree in a scientific discipline and at least ONE (1) year of relevant experience.
• Deep experience in managing and maintaining large mouse colonies, mouse genotyping, and the generation, execution, and interpretation of mouse experimental models, as well as experience with cell culture, PCR/qPCR/ddPCR, flow cytometry and/or animal research techniques.
• Ability to work independently and collaborate across multidisciplinary teams.
• Must be able to obtain and maintain a Federal or DoD “public trust”; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred.

What Would Be Nice To Have

• Outstanding interpersonal and time management skills.
• Strong organizational and communication skills, attention to detail, and the ability to collaborate in a fast‑paced translational research environment.
• Excellent verbal and written communication skills.
• Demonstrated experience in staff training and mentoring.

The annual salary range for this position is $74,000.00-$124,000.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.

What We Offer

Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits Include

• Medical, Rx, Dental & Vision Insurance
• Personal and Family Sick Time & Company Paid Holidays
• Parental Leave
• 401(k) Retirement Plan
• Group Term Life and Travel Assistance
• Voluntary Life and AD&D Insurance
• Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
• Transit and Parking Commuter Benefits
• Short-Term & Long-Term Disability
• Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
• Employee Referral Program
• Corporate Sponsored Events & Community Outreach
• Care.com annual membership
• Employee Assistance Program
• Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)
• Position may be eligible for a discretionary variable incentive bonus

About Guidehouse

Guidehouse is an Equal Opportunity Employer–Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.

Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.

If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at [e-mail]. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.