MES Engineer

GlaxoSmithKline; King of Prussia (Montgomery County); On-site; USD 80,000 - 110,000; Full time

Job summary

An established industry player is seeking a MES Engineer to enhance manufacturing execution systems in a biopharmaceutical setting. This role involves providing technical support for Emerson Syncade, ensuring compliance, and driving continuous improvement initiatives. You'll collaborate with various stakeholders to optimize system performance, troubleshoot issues, and contribute to the scaling of technology solutions. If you're passionate about leveraging technology to improve healthcare outcomes and thrive in a dynamic environment, this opportunity is perfect for you.

Benefits

Health Insurance

Retirement Plan

Paid Time Off

Flexible Working Hours

Employee Assistance Program

Wellness Programs

Qualifications

• Provide technical support for manufacturing execution systems.
• 3+ years experience with MES systems in Life Sciences.
• 2+ years in GMP manufacturing settings.

Responsibilities

• Support and optimize MES performance and integration.
• Collaborate with operations for system design and implementation.
• Troubleshoot and maintain Syncade and related systems.

Skills

Emerson Syncade

SQL

GMP Manufacturing

Troubleshooting

Continuous Improvement

Education

BS/BA in Engineering

4+ years of MES experience

Tools

Windows Server Administration

Database Administration

XML/XSL

Job description

Site Name: USA - Pennsylvania - King of Prussia
Posted Date: Apr 17 2025

The purpose of the MES Engineer is to provide intermediate level technical support of manufacturing execution systems (Syncade) in a biopharmaceutical manufacturing facility. Provide technical backstop support of daily operations and drive continuous improvement and scaling of the existing footprint.

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

• Provide support and technical subject matter expertise to the site’s deployments of Emerson Syncade (manufacturing execution system). Ensure the reliable performance and continuous improvement/optimization the MES footprint.
  • Recipe authoring, Equipment, Material, Order Management, software development and testing.
  • Troubleshoot plant floor MES execution and integration issues.
  • Change Control, Validation, and Qualification Management of system changes.
  • Compliance and inspection readiness of MES.
• Maintain and upkeep Syncade through administration and break/fix support of related systems, networks, integrations, databases, and accounts.
  • Able to query and assess the Syncade data warehouse (SQL).
  • Perform hotfix upgrades in Syncade. Includes assessing change impact, provisioning in kind, performing the upgrade, testing, and hypercare.
  • Understand SC Consumer, Business Integrator, Event Monitor, OPC Client/Server, Infobatch Report Design and Integration, and troubleshoot performance and function of each component as it relates to the complete MES solution design (including other integrated systems and operational context).
• Understand the flow of data among business and operational technology systems, with a focus on Syncade, including technical nuances as well as operational context to make sense of the end to end flow.
• Improve Department performance and posture through continuous improvement (e.g. procedural, way of working, capability, etc.).
• Contribute to further scaling of Syncade by providing key input to solution design as well as project/executional design. Contribute to related capital investments. Rationalize performance and investment with business impact.
• Collaborate with Operations and building stakeholders throughout the software or system development lifecycle: gather system/end user requirements; complete design, implementation, and testing/validation of changes; document changes; maintain and monitor the system; ensure end user readiness.
• Work in a way that models respect for safety and EHS, quality compliance, data integrity, and engineering standards.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• BS/BA in engineering, computer science, IT, or equivalent technical discipline
• OR 4+ years of MES experience in Life Sciences in lieu education
• 3+ years engineering, troubleshooting, and solutions design of Emerson Syncade , Körber/Werum PAS-X, Siemens Opcenter Execution Pharma (Simatic EBR), POMS, Rockwell PharmaSuite, or other Life Sciences focuse MES systems.
• 2+ years working in a GMP manufacturing setting

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• Windows Server Administration including
  • Active Directory and Security Models
  • TCP/IP Networking, Routing, Ports and Firewalls
  • Internet Information Services (IIS), Secure Website Administration, ASP
  • Remote Desktop Services
  • Event Monitoring, Services, Registry, Scripting Technologies such as vbscript
• Database Administration and Design (SQL)
• XML/XSL. Web services.
• Emerson SC Consumer, Business Integrator, and Event Monitor.
• SAP PPM Understanding, Use, and Integration
• OPC Client/Server Architecture and Troubleshooting
• S95/S88 Batch Execution Systems such as DeltaV Campaign Manager/Batch Executive/Batch Historian
• Informetric Systems Infobatch. XSLT.
• Able to function within team based organization.

#LI-GSK

Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

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