Lead Scientist, Spatial Multiomics & MPRA

Johnson & Johnson Innovative Medicine

Cambridge (MA)

On-site

USD 117,000 - 201,000

Full time

10 days ago
Application generator

Stand out for this role — generate a tailored resume and cover letter in about a minute.

Get past ATS filters

Job summary

Johnson & Johnson Innovative Medicine in Cambridge MA is seeking a Principal Scientist to advance spatial omics and functional genomics platforms for therapeutic discovery. The role blends hands-on experimentation with scientific leadership to build integrated multiomic workflows.

The candidate will lead design and execution of spatial profiling, MPRA development, and CRISPR-based perturbation studies, collaborating with computation teams to derive actionable insights for multiple discovery

Qualifications

  • Minimum of 6 years in biotech/pharma translational research environments.
  • Demonstrated leadership with publications, presentations, patents, or major technology contributions.
  • Experience across spatial omics, functional genomics, or both; ability to work across biology, tech, computation and therapy areas.

Responsibilities

  • Lead development and deployment of massively parallel reporter assays (MPRAs) with single-cell and spatial omics integration.
  • Design workflows connecting perturbation, reporter activity, and transcriptional profiling.
  • Scale emerging technologies to enhance therapeutic pathway discovery and translational research.
  • Collaborate with computational scientists to develop data standards and scalable analytics.

Skills

Spatial omics
Functional genomics
MPRAs
CRISPR screens

Education

PhD in Genetics/Genomics/ Molecular Biology or related
Postdoctoral training preferred

Job description

Johnson & Johnson Innovative Medicine in Cambridge MA is seeking a Principal Scientist to advance spatial omics and functional genomics platforms for therapeutic discovery. The role blends hands-on experimentation with scientific leadership to build integrated multiomic workflows.

The candidate will lead design and execution of spatial profiling, MPRA development, and CRISPR-based perturbation studies, collaborating with computation teams to derive actionable insights for multiple discovery

Get your free, confidential resume review.

or drag and drop your file here.

Similar jobs

Similar jobs worth comparing

Principal Scientist, Spatial Omics & Multiomics Platforms
Principal Scientist, Spatial Omics & Multiomics Platforms

6084-Janssen Research & Development, LLC Legal Entity • Cambridge (MA)

On-site
USD 117,000 - 201,000
Vacation & leave benefits
Retirement plan participation
Paid holidays
Principal Scientist, Spatial & Multiomics
Principal Scientist, Spatial & Multiomics

Johnson & Johnson Innovative Medicine • Spring House (PA)

On-site
USD 117,000 - 201,000
Retirement plan
Long‑term incentive program
Vacation 120 hours per year
Principal Scientist, Multiomics
Principal Scientist, Multiomics

6084-Janssen Research & Development, LLC Legal Entity • Cambridge (MA)

On-site
USD 117,000 - 201,000
Vacation & leave benefits
Retirement plan participation
Paid holidays
Scientific PMM: Lead Spatial Biology & Multiomics Strategy
Scientific PMM: Lead Spatial Biology & Multiomics Strategy

Bruker Spatial Biology • United States

On-site
USD 120,000 - 170,000
Lead, Spatial Biology & Multi-Omics Platforms
Lead, Spatial Biology & Multi-Omics Platforms

BioSpace • New York (NY)

On-site
USD 138,000 - 224,000
Bonus eligibility
401(k) plan
Health, dental, vision benefits
Principal Scientist, Multiomics
Principal Scientist, Multiomics

Johnson & Johnson Innovative Medicine • Cambridge (MA)

On-site
USD 117,000 - 201,000
Senior Scientist, Multi-Omic Data & AI for Target Discovery
Senior Scientist, Multi-Omic Data & AI for Target Discovery

Johnson & Johnson Innovative Medicine • Spring House (PA)

On-site
USD 109,000 - 175,000
Senior Scientist, Spatial Proteomics & Tissue Imaging
Senior Scientist, Spatial Proteomics & Tissue Imaging

Neara • Pleasanton (CA), Northern (KY)

Hybrid
USD 150,000 - 210,000
Imaging & Translational Profiling Lead
Imaging & Translational Profiling Lead

Novartis Group Companies • Cambridge (MA)

On-site
USD 139,000 - 257,000
Performance-based incentive
Comprehensive benefits package
Lead, Spatial Genomics & Long-Read Innovation
Lead, Spatial Genomics & Long-Read Innovation

Initial Therapeutics, Inc. • New York (NY)

On-site
USD 138,000 - 225,000
401(k) and pension
Vacation benefits
Medical, dental, and vision benefits