Lead MRD Bioinformatics Scientist

C2i Genomics; California (MO); On-site; USD 184,000 - 210,000; Full time

Job summary

Veracyte is seeking a Principal Bioinformatics Scientist to lead the bioinformatics strategy for MRD LDTs, shaping assay concepts from design to launch. You will own analytical validation, develop scalable pipelines, and partner with cross‑functional teams to deliver robust diagnostic insights for multiple indications.

The role requires deep NGS oncology assay expertise, ctDNA biology, and proven leadership in regulated environments, including CAP/CLIA.

Qualifications

• Ph.D. in Bioinformatics, Computational Biology, Genomics, Biostatistics, or closely related field.
• Minimum 8 years total relevant experience, with 5+ years in biotech/diagnostics/regulatory environments.
• Hands-on experience leading NGS-based assay development for clinical diagnostics.

Responsibilities

• Lead bioinformatics strategy for MRD assay design, development, and lifecycle management under CAP/CLIA.
• Develop and maintain production-grade bioinformatics pipelines for MRD analysis.
• Ensure compliance with CAP/CLIA, FDA, IVDR across development lifecycle.
• Collaborate with wet-lab, clinical, QA/RA, and software teams to align bioinformatics with assay design and regulatory expectations.

Skills

Python programming

NGS bioinformatics

Computational biology

Biostatistics

Data analysis pipelines

Regulated environments

Education

Ph.D. in Bioinformatics or related

8+ years total experience

Tools

AWS

R

Job description

Veracyte is seeking a Principal Bioinformatics Scientist to lead the bioinformatics strategy for MRD LDTs, shaping assay concepts from design to launch. You will own analytical validation, develop scalable pipelines, and partner with cross‑functional teams to deliver robust diagnostic insights for multiple indications.

The role requires deep NGS oncology assay expertise, ctDNA biology, and proven leadership in regulated environments, including CAP/CLIA.