Lead DMPK Scientist, Biologics & Small Molecules

Scorpion Therapeutics; Watertown (MA); On-site; USD 150,000 - 210,000; Full time

Job summary

Scorpion Therapeutics is seeking an experienced DMPK Scientist to lead PK/PD strategy across biologics and small molecules. You will design and interpret in vitro ADME and in vivo PK studies, guiding decisions throughout discovery and early development, including IND-enabling phases.

The role emphasizes cross-disciplinary collaboration, strong communication, and external CRO oversight to ensure timely, high-quality data generation for regulatory submissions.

Qualifications

• MS in DMPK/biology/chemistry or PhD with 5+ years in industry.
• Demonstrated expertise in large-molecule PK/PKPD and/or discovery/development.
• Strong ADME/PK/PKPD knowledge for small molecules.

Responsibilities

• Lead DMPK representative on biologics or small molecule projects; provide scientific leadership.
• Design, conduct, interpret, and report in vitro ADME, in vivo PK, and PK/PD studies.
• Develop and maintain compound selection criteria; drive decision making.

Skills

DMPK leadership

PK/PD expertise

ADME knowledge

Cross-disciplinary collaboration

Excellent communication

Education

MS in DMPK/Biology/Chemistry

PhD in related field

Job description

Scorpion Therapeutics is seeking an experienced DMPK Scientist to lead PK/PD strategy across biologics and small molecules. You will design and interpret in vitro ADME and in vivo PK studies, guiding decisions throughout discovery and early development, including IND-enabling phases.

The role emphasizes cross-disciplinary collaboration, strong communication, and external CRO oversight to ensure timely, high-quality data generation for regulatory submissions.