Lead Bioinformatics Scientist, MRD & NGS Oncology

Scorpion Therapeutics; South San Francisco (CA); On-site; USD 184,000 - 210,000; Full time

Job summary

Scorpion Therapeutics seeks a Principal Bioinformatics Scientist to lead NGS-based MRD assay development for cancer diagnostics in CAP/CLIA environments. You will oversee bioinformatics strategy, assay design, and validation, and mentor junior staff.

Based in San Diego or South San Francisco, the role requires ctDNA biology expertise, Python programming, and experience with regulated environments, with a salary range of $184K–$210K depending on location and experience.

Qualifications

• PhD in Bioinformatics, Genomics, or related field.
• 8+ years industry experience, incl. 5+ years in regulated healthcare/diagnostics.
• Extensive hands-on expertise in ctDNA biology and NGS assay development.
• Strong Python programming and SDLC familiarity.
• Experience in CAP/CLIA regulated environments.

Responsibilities

• Lead analytical validation, study design, and performance characterization.
• Develop and maintain production bioinformatics pipelines.
• Collaborate with wet-lab, clinical, quality, regulatory, and software teams.
• Contribute to regulatory documentation.
• Mentor junior staff and communicate complex data to stakeholders.

Skills

Python programming

SDLC best practices

Education

Ph.D. in Bioinformatics/Genomics

Tools

AWS workflow deployment

R proficiency

Databases

Job description

Scorpion Therapeutics seeks a Principal Bioinformatics Scientist to lead NGS-based MRD assay development for cancer diagnostics in CAP/CLIA environments. You will oversee bioinformatics strategy, assay design, and validation, and mentor junior staff.

Based in San Diego or South San Francisco, the role requires ctDNA biology expertise, Python programming, and experience with regulated environments, with a salary range of $184K–$210K depending on location and experience.