Lead Bioinformatics Core Lab: RNA-Seq & Single-Cell Analysis

Albany Medical Center; City of Albany (NY); Presencial; USD 77.000 - 119.000; Jornada completa

Descripción de la vacante

Albany Medical Center is seeking a Biostatistics/Bioinformatics Core Scientist to perform comprehensive genomic analyses and manage core facility operations within the Molecular & Cellular Physiology department. You will translate biological questions into computational analyses and deliver publication-ready results.

The role emphasizes end-to-end sequencing data analysis (bulk and single-cell), integration across modalities, and leadership in developing reproducible pipelines while coordinating

Formación

• A bachelor’s degree in biology, biochemistry, molecular biology, biomedical engineering or a related scientific field is required.
• Master's degree or PhD in bioinformatics, computational biology, genomics, biostatistics, molecular biology, or a related discipline preferred.
• Requires three (3) or more years of increasingly responsible experience in a laboratory or core facility operations.
• Five (5) or more years of increasingly responsible experience conducting in a research laboratory or shared research core environment laboratory research including operational or technical leadership with managerial experience is also preferred.

Responsabilidades

• Perform end-to-end bulk RNA-seq analysis, including quality control, alignment or quantification, differential expression, pathway enrichment, visualization, and biological interpretation.
• Analyze single-cell RNA-seq and spatial datasets, including quality control, normalization, integration, dimensionality reduction, clustering, cell-type annotation, differential expression, compositional analysis, and pathway-level interpretation.
• Perform ATAC-seq, CUT&Tag, and CUT&RUN analyses, including peak calling, differential accessibility or binding, genomic annotation, motif analysis, and integration with transcriptional datasets.
• Integrate datasets across experimental conditions, tissues, time points, species, and genomic modalities to identify biologically meaningful pathways, cell states, and regulatory mechanisms.
• Generate publication-quality figures, including UMAPs, heatmaps, dot plots, volcano plots, enrichment plots, genome-track visualizations, and integrated multiomic figures.
• Develop and maintain reproducible R, Python, and Linux analysis workflows and standardized core pipelines.
• Participate in meetings with investigators to present results and explain computational findings to researchers with different levels of bioinformatics experience.
• Contribute bioinformatics methods, figures, preliminary analyses, and technical language for manuscripts, abstracts, presentations, and grant applications.
• Evaluate and assist with the implementation of new computational methods and genomic technologies as the Bioinformatics Core expands.

Conocimientos

Genomics data analysis

Bioinformatics

Programming (R/Python)

Data visualization

Educación

Bachelor's degree in biology or related field

Master's degree in bioinformatics preferred

Herramientas

R

Python

Linux

Descripción del empleo

Albany Medical Center is seeking a Biostatistics/Bioinformatics Core Scientist to perform comprehensive genomic analyses and manage core facility operations within the Molecular & Cellular Physiology department. You will translate biological questions into computational analyses and deliver publication-ready results.

The role emphasizes end-to-end sequencing data analysis (bulk and single-cell), integration across modalities, and leadership in developing reproducible pipelines while coordinating