Lead Biocatalysis Scientist, Process Chemistry

BioSpace; North Chicago (IL); On-site; USD 140,000 - 190,000; Full time

Benefits offered by this job

Paid time off

Medical/dental/vision insurance

401(k) plan

Long-term incentive programs

Job summary

AbbVie, a leader in biopharmaceuticals, seeks a Process Chemistry scientist to invent and execute chemical processes for API development and toxicology support. You will drive enzyme-based solutions, leverage AI/ML, and lead teams across discovery and development to deliver safe, scalable manufacturing processes.

The role emphasizes innovation, cross-functional collaboration, and adherence to GxP standards in a fast-paced environment.

Qualifications

• PhD, MS, or BS in inorganic chemistry with relevant experience in biocatalysis.
• Experience with recombinant DNA techniques and protein expression.
• Experience with high-throughput experimentation (HTE) platforms and data analysis workflows.
• Experience applying AI/ML and data science to solve synthesis problems.

Responsibilities

• Contribute to setting and implementing strategies for solving complex synthetic problems in process development via biocatalytic methods.
• Identify and design enzymes, apply recombinant DNA techniques, express proteins, and engineer biocatalysts for new transformations in API process development.
• Leverage AI/ML tools, bioinformatics platforms, and HTE to accelerate enzyme screening and process development cycles.
• Lead project teams for process development and characterization of small molecules, peptides, ADCs, and other modalities.
• Connect unrelated concepts to generate new ideas and look for the next big win.
• Author and review technical reports, regulatory documents, patents, and publications; present findings at forums.
• Adhere to GxP, safety, and corporate standards.

Skills

Biocatalysis

Enzyme screening

Protein expression

Recombinant DNA techniques

AI/ML data science

Automation technologies

Leadership

Cross-functional collaboration

Education

Bachelor/Master/PhD in inorganic chemistry

Tools

HTE platforms

AI/ML data analysis

Job description

AbbVie, a leader in biopharmaceuticals, seeks a Process Chemistry scientist to invent and execute chemical processes for API development and toxicology support. You will drive enzyme-based solutions, leverage AI/ML, and lead teams across discovery and development to deliver safe, scalable manufacturing processes.

The role emphasizes innovation, cross-functional collaboration, and adherence to GxP standards in a fast-paced environment.