LC-MS Scientist, Biotherapeutics

Regeneron Pharmaceuticals, Inc.; Tarrytown (GA); On-site; USD 94,000 - 153,000; Full time

Job summary

Regeneron Pharmaceuticals in Tarrytown, NY, is seeking a Scientist to join the Analytical and Biological Mass Spectrometry Group (ABMS). The role focuses on LC-MS based characterization of biotherapeutics to support drug development, from early-stage candidates through regulatory submissions.

You will develop LC-MS methods, analyze monoclonal antibodies and related modalities, and collaborate across formulation, process development, and manufacturing teams.

Qualifications

• Bachelor’s or Master’s degree in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or a closely related field.
• Industrial or academic experience in LC-MS based analytical characterization of protein therapeutics
• Hands-on experience with advanced mass spectrometers, liquid chromatography, various separation technologies, and data processing software is desired
• Experience with intact mass analysis is a plus

Responsibilities

• Execute LC-MS based characterization of biotherapeutics to support drug development
• Develop LC-MS methods to characterize charge variants, size variants, and post-translational modifications
• Provide analytical support to cross-functional teams (formulation development, upstream/downstream process development, and manufacturing)
• Independently conduct sample preparation and LC-MS analyses in compliance with SOPs, and document experimental procedures and results in ELN
• Present data at group and project meetings; write technical reports, SOPs, and regulatory filing reports

Education

Bachelor’s or Master’s degree in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or a closely related field

Tools

LC-MS

Mass spectrometry instrumentation

Data processing software

Job description

Regeneron Pharmaceuticals in Tarrytown, NY, is seeking a Scientist to join the Analytical and Biological Mass Spectrometry Group (ABMS). The role focuses on LC-MS based characterization of biotherapeutics to support drug development, from early-stage candidates through regulatory submissions.

You will develop LC-MS methods, analyze monoclonal antibodies and related modalities, and collaborate across formulation, process development, and manufacturing teams.