Laboratory Manager – Electron Microscopy Core

University of Kansas Medical Center; Kansas City (KS); On-site; USD 58,000 - 86,000; Full time

Job summary

A forward-thinking institution is seeking a Laboratory Manager for its Electron Microscopy Core. This role involves guiding researchers in advanced electron microscopy techniques and ensuring optimal equipment performance. The ideal candidate will thrive in a collaborative research environment, managing data, training users, and maintaining high-resolution electron microscopes. This position offers an exciting opportunity to contribute to groundbreaking research and enhance the capabilities of a state-of-the-art facility. If you are passionate about advancing scientific discovery and have a strong background in microscopy, this is the perfect role for you.

Benefits

Health Insurance

Dental Insurance

Vision Insurance

Paid Time Off

Retirement Program

Life Insurance

Long-term Disability Insurance

Flexible Spending Accounts

Generous Employer Contributions

Paid Holidays

Qualifications

• 3+ years of lab experience with electron microscopy techniques.
• Strong understanding of cellular ultrastructure and protein biochemistry.

Responsibilities

• Plan and coordinate imaging related to TEM, SEM, and cryo-EM.
• Train users on electron microscopy technology and maintain training logs.

Skills

Electron Microscopy

Data Management

Sample Preparation

Communication Skills

Time Management

Attention to Detail

Education

Bachelor’s degree in life sciences

Master’s degree in life sciences

Tools

JEOL JEM 1400 TEM

TFS Vitrobot

cryoSPARC

Job description

Laboratory Manager – Electron Microscopy Core

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Laboratory Manager – Electron Microscopy Core

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Join to apply for the Laboratory Manager – Electron Microscopy Core role at University of Kansas Medical Center

Position Title:

Department:

RSC SOM KC Cryo EM

KIDDRC

Position Title:

Laboratory Manager – Electron Microscopy Core

Job Family Group:

Professional Staff

Job Description Summary:

The KUMC Electron Microscopy Core provides state-of-the-art equipment, infrastructure, and services to researchers across KU Medical Center and other regional research institutions. The Laboratory Manager will work in collaboration with the Scientific Director and EMC Managing Director to guide and train users across a wide range of electron microscopy techniques. This individual will support researchers using electron microscopy and cryo-electron microscopy imaging and sample preparation in a highly collaborative and interdisciplinary research environment. The individual will be expected to work independently with minimal supervision.

Job Description:

Key Roles and Responsibilities:

• Plans, coordinates and performs imaging and data management related to Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM) and Cryogenic Electron Microscopy (cryo-EM).

• Supports researchers within a core laboratory using appropriate Standard Operating Procedures (SOPs) for Electron Microscopy (EM) technologies, including:
• Sample preparation techniques, imaging, and data management related to TEM, SEM and cryo-EM.
• Sample fixation and staining using chemical fixatives, ultramicrotomy/sectioning, traditional EM sample staining techniques and processing.
• Plunge freezing and clipping of cryo-EM samples using vitrification equipment such as a TFS Vitrobot.
• Trains and manages the activities of all students, postdocs, staff scientists, and principal investigators using the Electron Microscopy Core. Trains and oversees all users on core electron microscopy technology and guide experimental design, including maintaining training logs.
  
  

Collects, manages and analyzes imaging data of samples for both cryo-EM and room-temp EM applications.

Collaborates with investigators to develop specialized services leveraging the Electron Microscopy Core’s specialized equipment.

Maintains Electron Microscopy systems and applications related to daily operations, including:

• Complete daily alignments and calibrations of JEOL JEM 1400 TEM, Glacios cryo-EM and other related equipment to ensure optimal instrument performance.
• Complete daily inspections to ensure laboratory equipment is in working order.
• Manage data, equipment usage, and billing records to ensure instruments are being used in accordance with core policies and requirements.
• Data analysis of cryo-EM micrographs using cryoSPARC and other related cryo-EM data processing software.
• Participates on the Electron Microscopy Core annual SOM Budget and Evaluation self-study.
• Manages data storage and retention following facility guidelines and data hygiene policies both internally and externally.
• Effectively communicates both verbally and through written platforms and conveys projected progress or core-related issues in a timely manner to the Scientific Director and EMC Managing Director.
• Reports instrument and related equipment usage for billing and record keeping purposes using project tracking software.
• Prioritizes access to projects and work within the Electron Microscopy Core
• Works in a professional, client-focused manner to identify and support the needs of the research programs serviced by the Electron Microscopy Core.
• Identify and work with administrative staff to procure necessary operational supplies and equipment.
• Administers lab safety with the EMC Managing Director, including delivering training, developing safety protocols, and maintaining safety and compliance documentation.
• Participates in lab compliance inspections including updating logs of cleaning events and adherence to compliance protocols with the Safety Office, interacting with regulators or their proxies, and maintaining and adhering to relevant SOPs. Maintains documentation of all approved protocols.
  
  

Education:

Required Qualifications:

• Bachelor’s degree in life sciences or a related physical science discipline OR an equivalent combination of education and relevant work experience on a year for year basis.
  
  

Work Experience:

• Three years of cumulative laboratory experience and demonstrate a thorough understanding and ability to manifest scientific rigor and reproducibility.
• Research experience demonstrating basic understanding of cellular ultrastructure, cell biology, and protein biochemistry
• Experience operating and maintaining high-resolution electron microscopes including TEM, SEM, and cryo-EM.
• Experience preparing samples for TEM, SEM, and cryo-EM, and a working knowledge of procedures such as negative stain, resin infiltration/embedding, thin sectioning, plunge freezing, clipping, etc.
  
  

Education:

Preferred Qualifications:

• Masters’ degree in a life science discipline preferred
  
  

Work Experience:

• Experience with proven track record of working collaboratively within a research laboratory setting.
• Experience writing, developing, and/or implementing laboratory protocols, SOPs, and experimental plans.
• Experience in data management and analysis; however, training within a supportive learning environment is available to willing candidates who wish to acquire these skills.
  
  

Skills:

• Ability to communicate results with other researchers through laboratory report writing, presentations, and/or peer-reviewed publications.
• Strong organizational skills including time management, record keeping, and data management.
• Ability to work independently within a supportive and collaborative environment.
• Ability to work collaboratively within a research laboratory setting.
• Attention to detail and ability to perform testing with tightly controlled consistency over time.
• Excellent communication and time management skills.
  
  

This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. It is only a summary of the typical functions of the job, not an exhaustive list of all possible job responsibilities, tasks, duties, and assignments. Furthermore, job duties, responsibilities and activities may change at any time with or without notice.

Required Documents:

• Resume
• Cover Letter
  
  

Comprehensive Benefits Package:

Coverage begins on day one for health, dental, and vision insurance and includes health expense accounts with generous employer contributions if the employee participates in a qualifying health plan. Employer-paid life insurance, long-term disability insurance, and various additional voluntary insurance plans are available. Paid time off, including vacation and sick, begins accruing upon hire, plus ten paid holidays. One paid discretionary day is available after six months of employment, and paid time off for bereavement, jury duty, military service, and parental leave is available after 12 months of employment. A retirement program with a generous employer contribution and additional voluntary retirement programs (457 or 403b) are available. https://www.kumc.edu/human-resources/benefits.html

Employee Type:

Regular

Time Type:

Full time

Rate Type:

Salary

Compensation Statement:

The pay range listed for this position is determined by our compensation program using market data and salary benchmarking. A combination of factors is considered in making compensation decisions including, but not limited to, education, experience and training, qualifications relative to the requirements of the position, and funding. At the University of Kansas Medical Center, a reasonable estimate for the starting pay range will be the minimum to midpoint of the posted range, taking into account the combination of factors listed above.

Pay Range:

$58,656.00 - $86,000.00

Minimum

$58,656.00

Midpoint

$72,328.00

Maximum

$86,000.00

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research, Analyst, and Information Technology

• Industries

  Higher Education

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