Instrumentation Calibration Lead - cGMP Systems

Genentech; San Francisco (CA); On-site; USD 85,000 - 157,000; Full time

Job summary

Genentech is seeking an Instrumentation Specialist to lead calibration, troubleshooting, repair, and maintenance of analytical instruments within a regulated manufacturing environment. You will mentor peers, oversee vendor activities, and ensure compliance with safety guidelines and SOPs.

You will collaborate with Manufacturing, Quality, Technology, and Engineering to maximize uptime and support advanced process control systems across start‑ups and ongoing operations.

Qualifications

• High school diploma or equivalent required; vocational/instrumentation training strongly preferred.
• Hands-on experience calibrating, troubleshooting, maintaining, and installing analytical instruments in a cGMP/cGxP environment.
• Technical expertise with process control systems, BAS, DCS, and loop controllers.
• Proficient with maintenance/calibration management systems and standard office applications.
• Strong safety knowledge, including Lock Out Tag Out procedures.

Responsibilities

• Perform advanced calibrations, repairs, and preventative maintenance on analytical and laboratory instrumentation to minimize downtime and support active plant operations.
• Oversee and manage vendor activities, including escorting external technicians and reviewing calibration, PM, and repair documentation.
• Provide technical leadership during the design, installation, validation, and commissioning of new instrumentation and complex process control systems.
• Monitor, trend, and analyze instrument data using BAS and DCS to implement corrective and preventative actions.
• Develop and refine operational documentation including calibration procedures, job plans, technical reports, and SOPs.
• Mentor and train peer craftspeople and assist management with task coordination and project execution.
• Lead multidisciplinary collaboration across Manufacturing, Quality, and Engineering teams to support system start-ups and address technical challenges.

Skills

Calibrations

Repairs

Preventative maintenance

Vendor management

Technical leadership

Instrument data analysis

Documentation

Mentoring

Process control systems

BAS/DCS knowledge

Education

High school diploma or equivalent

Tools

Calibration management systems

Office software

Job description

Genentech is seeking an Instrumentation Specialist to lead calibration, troubleshooting, repair, and maintenance of analytical instruments within a regulated manufacturing environment. You will mentor peers, oversee vendor activities, and ensure compliance with safety guidelines and SOPs.

You will collaborate with Manufacturing, Quality, Technology, and Engineering to maximize uptime and support advanced process control systems across start‑ups and ongoing operations.