Instrumentation/Calibration Technician

Genentech; San Francisco (CA); On-site; USD 85,000 - 157,000; Full time

Job summary

Genentech is seeking an Instrumentation Specialist to lead calibration, troubleshooting, repair, and maintenance of analytical instruments within a regulated manufacturing environment. You will mentor peers, oversee vendor activities, and ensure compliance with safety guidelines and SOPs.

You will collaborate with Manufacturing, Quality, Technology, and Engineering to maximize uptime and support advanced process control systems across start‑ups and ongoing operations.

Qualifications

• High school diploma or equivalent required; vocational/instrumentation training strongly preferred.
• Hands-on experience calibrating, troubleshooting, maintaining, and installing analytical instruments in a cGMP/cGxP environment.
• Technical expertise with process control systems, BAS, DCS, and loop controllers.
• Proficient with maintenance/calibration management systems and standard office applications.
• Strong safety knowledge, including Lock Out Tag Out procedures.

Responsibilities

• Perform advanced calibrations, repairs, and preventative maintenance on analytical and laboratory instrumentation to minimize downtime and support active plant operations.
• Oversee and manage vendor activities, including escorting external technicians and reviewing calibration, PM, and repair documentation.
• Provide technical leadership during the design, installation, validation, and commissioning of new instrumentation and complex process control systems.
• Monitor, trend, and analyze instrument data using BAS and DCS to implement corrective and preventative actions.
• Develop and refine operational documentation including calibration procedures, job plans, technical reports, and SOPs.
• Mentor and train peer craftspeople and assist management with task coordination and project execution.
• Lead multidisciplinary collaboration across Manufacturing, Quality, and Engineering teams to support system start-ups and address technical challenges.

Skills

Calibrations

Repairs

Preventative maintenance

Vendor management

Technical leadership

Instrument data analysis

Documentation

Mentoring

Process control systems

BAS/DCS knowledge

Education

High school diploma or equivalent

Tools

Calibration management systems

Office software

Job description

The Position

This role is a valuable part of our Instrument Services and Maintenance team, which is committed to achieving our mission of ensuring uninterrupted plant operations and precise analytical measurement in a regulated manufacturing environment. As a member of this team, you will have the opportunity to collaborate closely with key stakeholders across Manufacturing, Quality, Technology, and Engineering. Together, we focus on maintaining compliance, maximizing equipment uptime, and supporting state-of-the-art process control systems to deliver reliable healthcare products to patients.

The Opportunity

As an Instrumentation Specialist, you will provide technical leadership in the calibration, troubleshooting, repair, and maintenance of advanced analytical and laboratory instruments within a cGMP/cGxP environment. In this role, you will ensure total equipment reliability, mentor peer craftspeople, and oversee vendor activities while maintaining strict compliance with safety guidelines and standard operating procedures.

• Perform advanced calibrations, repairs, and preventative maintenance on analytical and laboratory instrumentation to minimize downtime and support active plant operations.
• Oversee and manage vendor activities, including escorting external technicians in lab areas and rigorously reviewing all calibration, PM, and repair documentation.
• Provide technical leadership and oversight during the design, installation, validation, and commissioning of new instrumentation and complex process control systems.
• Monitor, trend, and analyze instrument data using Building Automation Systems (BAS) and Distributed Control Systems (DCS) to implement corrective and preventative actions.
• Develop and refine operational documentation, including comprehensive calibration procedures, job plans, technical reports, and SOPs.
• Mentor and train peer craftspeople to build departmental proficiency while assisting management with task coordination and project execution.
• Lead multidisciplinary collaboration across Manufacturing, Quality, and Engineering teams to support system start-ups and address technical challenges.

Who You Are

• High school diploma or equivalency required; vocational training, technical certifications, or specialized factory training in instrumentation is strongly preferred.
• Proven hands-on experience in calibrating, troubleshooting, maintaining, and installing analytical and laboratory instruments in a cGMP/cGxP regulated environment.
• Demonstrated technical expertise with process control systems, Building Automation Systems (BAS), Distributed Control Systems (DCS), and loop controllers.
• Proficient computer skills with experience operating maintenance/calibration management systems, standard office applications, and corporate intranets.
• Strong understanding of safety protocols, including active execution of Lock Out Tag Out (LOTO) procedures and safe operation of shop tools.
• Exceptional leadership and communication skills, with a demonstrated ability to mentor peers, present to multidisciplinary project teams, and coordinate vendor operations.
• Strong analytical and problem-solving abilities, with experience preparing technical job plans, SOPs, and system validation documentation.

Relocation benefits are not available for this job posting.

Pay transparency

The expected salary range for this position based on the primary location of California is $84,800.00- $157,400.00. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.