In Vivo Pharmacology Assistant

System One, Inc.; Boston (MA); Presencial; USD 72.000 - 79.000; A tiempo parcial

Descripción de la vacante

System One, Inc. in Boston is seeking an In Vivo Pharmacology Assistant for a contract role onsite. You will join a gene therapy in vivo pharmacology lab to perform experiments supporting discovery and optimization of novel therapeutic candidates for genetic medicines.

The position requires a B.S./M.S. in life sciences and 3-5 years in pharma or CRO, with hands-on rodent handling, dosing, blood collection, necropsies, tissue processing, and data analysis.

Formación

• B.S./M.S. in life sciences or related field required.
• 3-5 years in pharma or CRO environment preferred.
• Hands-on rodent handling, dosing and blood collection in mice/rats required.
• Experience with necropsies, tissue dissection, processing and trimming.
• Ability to adapt to changing platform needs and provide occasional night/weekend hours.
• Strong communication and collaboration skills across teams.

Responsabilidades

• Design and execute in vivo pharmacology experiments in rodent models.
• Assist development and characterization of in vivo models.
• Collaborate with Preclinical, toxicology, and PK/PD teams to translate discovery to development.
• Provide clear written and verbal study reports and attend meetings.
• Maintain electronic notebook and ensure compliance with procedures and GD practices.
• Ensure adherence to health and safety regulations.

Conocimientos

Rodent handling

Dosing & blood collection

Necropsies & tissue processing

Experiment design & interpretation

Data analysis & visualization

Documentation & GMP practices

Educación

B.S./M.S. in life sciences

Descripción del empleo

Job Title: In Vivo Pharmacology Assistant
Location: Boston, Massachusetts
Type: Contract
Compensation: $52- $57.25/hr
Work Model: Onsite
Hours: Monday-Friday 8am to 5pm

Overview

The In Vivo Pharmacology Assistant will participate in the Gene Therapy in vivo pharmacology lab to execute experiments in support of the discovery and optimization of novel therapeutic candidates for genetic medicines.

Responsibilities

• Work with team leads to design and execute in vivo pharmacology experiments to characterize activity, distribution, and clearance of genetic medicines in rodent models, including mice, rats, and immuno-compromised animals.
• Assist in the development and characterization of novel in vivo models.
• Collaborate with cross-functional partners (Preclinical, toxicology, PK/PD modelling) to ensure the translation from discovery to development.
• Provide written and verbal communication of work in study reports and team meetings.
• Keep and maintain accurate and timely documentation of all practical work: completion of electronic notebook in alignment with company procedure quality standards and Good Documentation Practices.
• Ensure compliance with all health and safety regulations.

Requirements

• B.S/MS in life sciences (e.g., biology, neuroscience, or related field)
• 3-5 years experience working in pharmaceutical industry or contract research organization.
• Hands on experience of rodent handling, dosing, and blood collection of mice and rats including but not limited to: subcutaneous (SC), intravenous (IV), & intraperitoneal (IP) injections, and submandibular, venipuncture, & cardiac puncture bleeds.
• Experience with gross necropsies, tissue dissection, and trimming and processing.
• Ability to adapt and exercise flexibility for changing platform needs, workflows, and projects including the availability to provide the occasional night, weekend, or holiday hours.
• Ability to craft, complete and interpret experiments independently, and to advance scientific understanding.
• Excellent communication skills and effective in collaborating across functional boundaries and in team environment.
• Strong organization skills, attention to detail, critical thinking, multitasking, desire to learn new techniques and contribute to innovative projects in a fast-paced working environment.
• Experience in processing, organizing, analyzing and visualizing data and information from disparate sources and ability to extract insight from data.

System One, and its subsidiaries including Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.