Scientist

Binding Minds Inc. (Certified Disability Owned Business Enterprise); Boston (MA); On-site; USD 85,000 - 130,000; Full time

Job summary

Binding Minds Inc. in the United States is seeking an in vivo pharmacology Scientist/Senior Scientist/Principal Scientist to participate in the Gene Therapy in vivo pharmacology lab. You will execute experiments supporting discovery and optimization of therapeutic candidates for genetic medicines.

The role involves designing robust animal studies, collaborating with cross-functional teams, and maintaining rigorous documentation while ensuring safety and regulatory compliance.

Qualifications

• B.S./M.S. in life sciences or 3–5 years of pharmaceutical industry or CRO experience.
• Hands-on rodent handling, dosing and blood collection in mice/rats including SC, IV, IP injections and various puncture methods.
• Experience with tissue dissection, necropsies and processing.
• Ability to design and interpret experiments independently and contribute to scientific understanding.
• Excellent communication and cross-functional collaboration skills.

Responsibilities

• Design and execute in vivo pharmacology experiments to characterize activity, distribution and clearance of genetic medicines in rodent models.
• Assist in development and characterization of in vivo models for clients.
• Collaborate with Preclinical, toxicology and PK/PD teams to translate discovery to development.
• Provide written and verbal communication in study reports and meetings.
• Maintain accurate documentation per Good Documentation Practices.
• Ensure compliance with health and safety regulations.

Skills

Rodent handling

Necropsy skills

Adaptability

Independent experimentation

Communication

Organization

Data processing/visualization

Education

B.S./M.S. in life sciences or 3–5 years pharma/CRO experience

Job description

• Work with team leads to design and execute in vivo pharmacology experiments to characterize activity, distribution, and clearance of genetic medicines in rodent models, including mice, rats, and immuno-compromised animals.
• Assist in the development and characterization of Client in vivo models.
• Collaborate with cross-functional partners (Preclinical, toxicology, PK/PD modelling) to ensure the translation from discovery to development.
• Provide written and verbal communication of work in study reports and team meetings.
• Keep and maintain accurate and timely documentation of all practical work: completion of electronic notebook in alignment with Lilly procedure quality standards and Good Documentation Practices.
• Ensure compliance with all health and safety regulations.

Quals--

Position Summary:

The in vivo pharmacology Scientist/Senior Scientist/Principal Scientist will participate in the Gene Therapy in vivo pharmacology lab to execute experiments in support of the discovery and optimization of Client therapeutic candidates for genetic medicines.

Basic Qualifications:

• B.S/MS in life sciences (e.g., biology, neuroscience, or related field) or 3-5 years experience working in pharmaceutical industry or contract research organization.

Additional Skills/Preferences:

• Hands on experience of rodent handling, dosing, and blood collection of mice and rats including but not limited to: subcutaneous (SC), intravenous (IV), & intraperitoneal (IP) injections, and submandibular, venipuncture, & cardiac puncture bleeds.
• Experience with gross necropsies, tissue dissection, and trimming and processing.
• Ability to adapt and exercise flexibility for changing platform needs, workflows, and projects including the availability to provide the occassional night, weekend, or holiday hours.
• Ability to craft, complete and interpret experiments independently, and to advance scientific understanding.
• Excellent communication skills and effective in collaborating across functional boundaries and in team environment.
• Strong organization skills, attention to detail, critical thinking, multitasking, desire to learn new techniques and contribute to innovative projects in a fast-paced working environment.
• Experience in processing, organizing, analyzing and visualizing data and information from disparate sources and ability to extract insight from data.