Scientist, In Vivo Pharmacology

Mykelly; Thousand Oaks (CA); On-site; USD 72,000 - 76,000; Full time

Job summary

Kelly Science & Clinical is seeking a Scientist, In Vivo Pharmacology for a contract position in Thousand Oaks, CA. The role centers on survival rodent models, ICV dosing, CSF collection, and PK/PD analyses to evaluate therapeutic candidates.

Requirements include a PhD/MD/BS+ with 5+ years of hands-on animal research, strong technical skills in survival surgery, dosing, and data integrity, plus effective written and verbal communication for cross-functional teams.

Qualifications

• Advanced degree in neuroscience, pharmacology, or related discipline.
• Hands-on animal research experience with survival rodent models.
• Experience with dosing, sample collection, and data integrity.

Responsibilities

• Perform survival rodent surgery and ICV dosing with CSF collection.
• Identify animal models and conduct studies to evaluate therapeutics.
• Design and execute in vivo pharmacology studies (PK/PD, efficacy).
• Handle rodents, collect blood, perform dosing routes, and conduct behavior tests.
• Maintain accurate records and comply with IACUC and AAALAC standards.
• Collaborate with biology and chemistry teams on project goals.

Skills

Survival rodent surgery

Rodent handling

Dosing & sample collection

PK/PD studies

Data integrity

Cross-functional collaboration

Verbal & written communication

Education

B.S., M.S., or PhD in neuroscience or pharmacology

Tools

Microsoft Office

GraphPad Prism

Electronic lab notebooks

Job description

Scientist, In Vivo Pharmacology

Kelly® Science & Clinical is seeking an Scientist, In Vivo Pharmacology for a contract position at a cutting-edge client in Thousand Oaks, CA. If you're passionate about bringing the latest scientific discoveries to life and are ready to take the next step in your career, trust The Experts at Hiring Experts.

Pay: $52-55/hour

Schedule: Mon-Fri Full-time, onsite

Overview

This client is focused on developing novel medicines for unmet patient needs and creating innovative therapies for eligible patients. The team combines expert knowledge with scientific approaches to improve the health of patients with life-threatening diseases.

Responsibilities

• Perform survival rodent surgery, including intracerebroventricular (ICV) dosing and cerebrospinal fluid (CSF) collection.
• Identify appropriate animal models and conduct studies using biological and functional readouts to evaluate therapeutic candidates.
• Design, plan, and execute in vivo pharmacology studies, including early exploratory models, tolerability, PK/PD, and efficacy.
• Perform in vivo procedures, including rodent handling, blood collection, IV, IP, SC, and PO dosing, behavioral assessment, necropsy, and tissue harvesting in accordance with approved IACUC protocols and AAALAC guidelines.
• Manage animal breeding and disease model colonies by setting up and monitoring litters, genotyping, and assessing phenotypes.
• Maintain accurate, complete, and compliant records of experimental procedures and animal use.
• Provide daily care and monitoring of laboratory animals in compliance with institutional standards.
• Collaborate closely with multidisciplinary teams, including biology and chemistry functions.

Qualifications

• B.S., M.S., or PhD in neuroscience, pharmacology, or a related discipline, with at least 5 years of hands‑on animal research experience.
• Strong technical skills in survival rodent surgery, rodent handling, dosing, and biological sample collection.
• Experience running tolerability, PK/PD, and efficacy studies in rodents.
• Working knowledge of laboratory operations, equipment, and vivarium safety standards.
• Working knowledge of rodent behavioral testing, such as von Frey, rotarod, Morris water maze, and Y-maze.
• Proficiency with standard laboratory software, such as Microsoft Office, GraphPad Prism, and electronic lab notebooks.
• Meticulous attention to detail and a firm commitment to data integrity.
• Clear written and verbal communication, including the ability to present data to cross-functional audiences.
• A collaborative approach and the ability to work effectively across teams.