Senior Research Associate, In Vivo Pharmacology (Contractor)

Legend Biotech; Philadelphia (Philadelphia County); On-site; USD 80,000 - 100,000; Full time

Benefits offered by this job

Medical, dental, and vision insurance

401(k) retirement plan with company match

Paid parental leave

Generous paid time off policy

Flexible spending and health savings accounts

Job summary

A biotechnology company is seeking a Senior Research Associate in Philadelphia to perform preclinical in vivo pharmacology and toxicology studies. Candidates should have a Master’s or Bachelor’s degree in biological sciences and at least 5 years of relevant laboratory experience. Responsibilities include conducting in vitro and in vivo studies, maintaining lab instruments, and collaborating with team members to advance pipeline projects. A strong sense of teamwork and attention to detail are essential for this role, which offers significant benefits and a comprehensive healthcare package.

Qualifications

• 5 years’ experience in a biological laboratory setting, ideally industry-focused.
• Ability to handle mice confidently, essential for in vivo studies.
• Strong attention to detail and multitasking abilities.

Responsibilities

• Execute various in vitro experiments including cell culture and functional analysis.
• Support in vivo animal studies including management of test article dosing.
• Maintain lab instruments and ensure quality of experiments.

Skills

Cell culture and cell‑based function analysis

In vivo study experience

Molecular biology skills

Organizational skills

Mouse handling and procedures

Education

Master’s or bachelor’s degree in biological sciences

Tools

ELISA

Flow cytometry

qPCR

Job description

Senior Research Associate, In Vivo Pharmacology (Contractor)

Location: Philadelphia, PA

Contract Duration: 12 months

Role Overview

This position will perform preclinical in vivo pharmacology and toxicology studies to support pipeline advancement. The ideal candidate will have experience in biology and oncology and in vivo studies with animal models. The successful candidate will work in a collaborative environment, supporting multiple projects by conducting various in vitro and in vivo laboratory experiments.

Key Responsibilities

• Work together with other team members to execute various in vitro experiments including cell culture and cell functional analysis, human PBMC isolation, ddPCR, flow‑cytometry analysis for biomarkers.
• Support in vivo animal studies including management of mouse colony, test article dosing through injections of intravenous, intraperitoneal and subcutaneous; tumor measurement through caliber and bioluminescent imaging; processing and analyzing various animal samples, including blood, tumor and tissues from mice and NHP.
• Lab instrument maintenance.

Requirements

• Master’s or bachelor’s degree in biological sciences (Immunology, cell biology, cancer biology, etc.).
• 5 years’ experience in a biological laboratory setting (industry preferred).
• Cell culture and cell‑based function analysis; experience in ELISA and flow‑cytometry is required.
• In vivo study experience is required; ability to handle mice confidently is essential.
• Molecular biology skills such as DNA and RNA extraction, RT‑PCR and ddPCR, etc.
• Sense of ownership and integrity of work; demonstrated ability to work as part of a team.
• Demonstrated organizational skills including attention to detail and multitasking.
• Mouse handling and procedures (bleeding, injection, in‑vivo imaging, tissue dissection and analysis), cell culture and function analysis, multi‑color flow cytometry, ELISA, qPCR, multiplexed cytokine analysis assays (MSD and Luminex); not allergic to lab animals.

Benefits

We are committed to creating a workplace where employees can thrive – both professionally and personally. Highlights include medical, dental, and vision insurance; a 401(k)‑retirement plan with company match that vests fully on day one; equity and stock options for eligible roles; eight weeks of paid parental leave after three months of employment; paid time off policy including 15 vacation days, 5 personal days, 5 sick days, 11 U.S. national holidays, and 3 floating holidays; flexible spending and health savings accounts; life and AD&D insurance; short‑ and long‑term disability coverage; legal assistance; supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance; commuter benefits; family planning and care resources; well‑being initiatives; and peer‑to‑peer recognition programs.

EEO Statement

Legend Biotech is a proud equal‑opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is Legend’s policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by applicable law.

Employment is at‑will and may be terminated at any time with or without cause or notice by the employee or the company. Legend may adjust base salary or other discretionary compensation at any time based on individual, team, performance, or market conditions.

Legend Biotech maintains a drug‑free workplace.