In Vitro Antibody Discovery Lead, Principal Scientist

Boehringer Ingelheim Pharmaceuticals, Inc.; Ridgefield (CT); On-site; USD 150,000 - 190,000; Full time

Job summary

Boehringer Ingelheim is seeking a Senior Principal Scientist or Principal Scientist to lead the in vitro antibody discovery team in Ridgefield, CT. You will define innovative in vitro strategies for phage and yeast display, drive lead identification, and advance discovery workflows with automation, NGS, and AI/ML enabled approaches, while mentoring staff and contributing to external scientific visibility.

The role emphasizes platform stewardship, collaboration with cross-functional groups, and

Qualifications

• PhD with 7+ years in related industry field.
• 4–6 years of experience leading employees, projects, and leaders.

Responsibilities

• Lead a scientific team generating novel antibodies using in vitro discovery platforms (phage and yeast display).
• Design high diversity antibody libraries for lead identification and maturation.
• Develop in vitro discovery strategies integrating automation, high throughput screening, and NGS-guided hit prioritization.
• Incorporate AI/ML guided sequence design and automate workflows.
• Maintain external scientific visibility through publications and collaborations.

Skills

Team leadership

Project management

Scientific communication

Biotherapeutics knowledge

Education

PhD in related field

Tools

Phage display

Yeast display

NGS analysis

Geneious

Bioinformatics tools

Job description

Boehringer Ingelheim is seeking a Senior Principal Scientist or Principal Scientist to lead the in vitro antibody discovery team in Ridgefield, CT. You will define innovative in vitro strategies for phage and yeast display, drive lead identification, and advance discovery workflows with automation, NGS, and AI/ML enabled approaches, while mentoring staff and contributing to external scientific visibility.

The role emphasizes platform stewardship, collaboration with cross-functional groups, and