High-Throughput Chemistry Scientist - Discovery & Automation

Iambic; San Diego (CA); On-site; USD 113,000 - 156,000; Full time

Benefits offered by this job

Competitive pay

Company paid healthcare

401K matching

Uncapped vacation

State-of-the-art facility

Onsite gym

Job summary

Iambic Therapeutics in San Diego, CA is seeking a Research Scientist to join its Discovery Chemistry team. You will design, optimize, and execute high-throughput experiments to accelerate compound library campaigns using our automated platforms.

The role requires a Ph.D. in Organic Chemistry or MS with substantial industry experience, hands-on HT chemistry, and a collaborative mindset across biology, software, and automation teams.

Qualifications

• Ph.D. in Organic Chemistry or MS in Organic Chemistry with extensive industry experience.
• Strong command of modern organic synthetic methods.
• Direct hands-on experience with High Throughput Chemistry and/or Parallel Synthesis.
• Experience with laboratory automation, liquid handling robotics, and automated analytical and purification systems.
• Ability to thrive in a fast-paced, highly collaborative research environment.
• Excellent written and verbal communication skills; ability to convey complex concepts clearly.

Responsibilities

• Design and execute parallel synthetic methods to generate large, high-quality compound libraries.
• Develop and optimize novel synthetic methodologies with a focus on automation compatibility and HTE scalability.
• Apply developed routes from bench-scale to high-throughput automated processes.
• Oversee operation and advancement of the chemistry toolkit and automated synthesis equipment.
• Analyze library data and communicate results to cross-functional teams.
• Ensure safety protocols and ELN data recording practices.
• Collaborate as part of an interdisciplinary team across chemistry, biology, software, and automation.
• Identify bottlenecks and troubleshoot automated processes to maintain business continuity.

Job description

Iambic Therapeutics in San Diego, CA is seeking a Research Scientist to join its Discovery Chemistry team. You will design, optimize, and execute high-throughput experiments to accelerate compound library campaigns using our automated platforms.

The role requires a Ph.D. in Organic Chemistry or MS with substantial industry experience, hands-on HT chemistry, and a collaborative mindset across biology, software, and automation teams.