Research Scientist — High-Throughput Chemistry & Automation

Iambic Therapeutics, Inc; San Diego (CA); Sur place; USD 120 000 - 180 000; Plein temps

Avantages offerts par ce poste

Company paid healthcare

401K matching

Flexible spending accounts

Uncapped vacation

Voluntary life insurance

Résumé du poste

Iambic Therapeutics, Inc. in San Diego, CA is seeking a Research Scientist to lead design and optimization of high-throughput synthetic strategies within Discovery Chemistry.

You will drive parallel synthesis, automate workflows, and collaborate across biology, AI/ML, and software teams to accelerate library campaigns. Ideal candidates hold a PhD in Organic Chemistry with relevant industry experience or an MS with substantial industry experience; strong communication and a collaborative mindset

Qualifications

• Ph.D. in Organic Chemistry with 0-5 years of industry experience or MS in Organic Chemistry with a minimum of 8 years of industry experience.
• Strong command of modern organic synthetic methods.
• Direct hands-on experience with High Throughput Chemistry and/or Parallel Synthesis.
• Experience with laboratory automation, liquid handling robotics, and automated analytical and purification systems.
• Ability to thrive in a fast-paced, highly collaborative, and dynamic research environment.
• Excellent written and verbal communication skills; must be able to articulate complex scientific concepts, technical challenges, and results clearly and concisely to diverse audiences.
• Proven ability to thrive in a fast-paced, high-volume environment where priorities and synthetic targets may shift rapidly based on biological data.

Responsabilités

• Design and execute parallel synthetic methods to generate large, high-quality compound libraries.
• Identify, develop, and optimize novel synthetic methodologies with a focus on automation compatibility and HTE scalability.
• Apply newly developed synthetic routes from traditional bench-scale chemistry to robust, high-throughput, and automated processes.
• Oversee the operation, maintenance, and continuous advancement of our chemistry toolkit and automated synthesis equipment.
• Analyze research outcomes and library compound data and clearly communicate results and findings to cross-functional project teams.
• Ensure all laboratory work is conducted in accordance with established safety protocols and best laboratory and ELN data recording practices.
• Function as a core member of an interdisciplinary scientific team (chemistry, biology, software, and automation).
• Proactively identify bottlenecks, troubleshoot automated processes, and develop solutions to ensure business continuity.

Connaissances

High Throughput Chemistry

Automation experience

Parallel Synthesis

Laboratory automation

Communication skills

Formation

PhD in Organic Chemistry

MS in Organic Chemistry

Outils

Liquid handling robotics

Automated analytical systems

Purification systems

Description du poste

Iambic Therapeutics, Inc. in San Diego, CA is seeking a Research Scientist to lead design and optimization of high-throughput synthetic strategies within Discovery Chemistry.

You will drive parallel synthesis, automate workflows, and collaborate across biology, AI/ML, and software teams to accelerate library campaigns. Ideal candidates hold a PhD in Organic Chemistry with relevant industry experience or an MS with substantial industry experience; strong communication and a collaborative mindset