Senior Scientist, High-Throughput Chemistry (Drug Discovery)

Otsuka Pharmaceutical Companies (U.S.); Boston (MA); On-site; USD 120,000 - 180,000; Full time

Job summary

Jnana Therapeutics, a wholly owned subsidiary of Otsuka Pharmaceutical, is a clinical-stage biotech company located in Boston. We are seeking a Scientist for our Discovery Chemistry group to advance drug discovery programs against hard-to-drug targets using the RAPID chemoproteomics platform.

You will execute high-throughput chemistry, develop new reactions for direct-to-biology chemistry, and help build automation and a robust HT chemistry function.

Qualifications

• Ph.D. in Medicinal Chemistry or Organic Chemistry with 3+ years industry experience.
• Experience in parallel synthesis, liquid handling, and high-throughput experiments.

Responsibilities

• Execute direct-to-biology, high-throughput chemistry to support the platform
• Develop and optimize new reactions for direct-to-biology chemistry
• Establish high-throughput chemistry function and planning/build out of laboratory automation
• Utilize synthetic expertise to design and execute synthesis of target molecules
• Work closely with external chemistry CRO teams to synthesize target molecules
• Work collaboratively across scientific disciplines on multiple projects
• Proactively engage in brainstorming and the generation of new ideas across projects
• Assist in preparing patent applications and publications
• Maintain a safe and productive laboratory environment

Skills

High-throughput chemistry

Direct-to-biology chemistry

Synthesis design

Lab automation

Cross-disciplinary collaboration

Communication skills

Education

Ph.D. in Medicinal Chemistry or Organic Chemistry

Tools

Liquid handling systems

Automation platforms

Job description

Jnana Therapeutics, a wholly owned subsidiary of Otsuka Pharmaceutical, is a clinical-stage biotech company located in Boston. We are seeking a Scientist for our Discovery Chemistry group to advance drug discovery programs against hard-to-drug targets using the RAPID chemoproteomics platform.

You will execute high-throughput chemistry, develop new reactions for direct-to-biology chemistry, and help build automation and a robust HT chemistry function.