Global Transformation Methodology & PMO Lead

Scorpion Therapeutics; Lexington (MA); On-site; USD 120,000 - 170,000; Full time

Job summary

Takeda seeks a Transformation Methodology Lead to define, build, and maintain end-to-end transformation methodologies and governance across the organization from Lexington, MA. You will establish a common delivery framework, set standards for business case development, milestone planning, risk management, and reporting, and drive measurable improvements in projects' value realization.

The role requires 5+ years in regulated pharma or similar environment, plus strong Power Platform fluency and

Qualifications

• Experience developing/implementing transformation methodologies, PMO standards, governance frameworks, or structured delivery models.
• 5+ years in global pharmaceutical industry or another highly regulated environment.
• Digital fluency with Microsoft Power Platform (Power Apps, Power Automate, Dataverse, Power BI).
• Strong analytical/problem-solving skills; ability to translate insights into practical improvements.
• Bachelor's degree (life sciences/business/engineering or related) or equivalent experience.

Responsibilities

• Define, build, and maintain the end-to-end transformation methodology (lifecycle stages, decision points, templates, standards, quality gates).
• Establish a common delivery framework and minimum standards across sites/functions.
• Define standards for business case development, scope, milestone planning, risk/issue management, dependency tracking, benefits realization, and performance reporting.
• Ensure initiatives are structured, measurable, and aligned to strategic priorities with clear ownership/accountability.
• Evolve the operating model, methodology, and standards; use portfolio metrics, dashboards, and executive reporting.
• Establish governance routines (decision rights, escalation paths, accountability), and lead governance checkpoints/exception management.
• Monitor adherence to methodologies and strengthen controls/standards/governance; standardize/simplify ways of working.
• Support data cleaning/ontology alignment/master data readiness; enable compliant, well-documented execution in a regulated environment.
• Maintain version control and knowledge assets; capture lessons learned and drive continuous improvement.

Skills

Transformation methodology

PMO standards

Governance frameworks

Structured delivery models

Analytical/problem solving

Education

Bachelor's degree (life sciences/business/engineering or related)

Tools

Power Apps

Power Automate

Dataverse

Power BI

Job description

Takeda seeks a Transformation Methodology Lead to define, build, and maintain end-to-end transformation methodologies and governance across the organization from Lexington, MA. You will establish a common delivery framework, set standards for business case development, milestone planning, risk management, and reporting, and drive measurable improvements in projects' value realization.

The role requires 5+ years in regulated pharma or similar environment, plus strong Power Platform fluency and