Global Clinical Ops Transformation & Performance Lead

Vertex Pharmaceuticals LLC; United States; On-site; USD 255,000 - 383,000; Full time

Benefits offered by this job

Medical, dental, and vision benefits

Generous paid time off including会社hols

Educational assistance and studentloan

Commuting subsidy

Job summary

Vertex Pharmaceuticals LLC in the United States seeks an Executive Director of Performance Excellence & Business Transformation for Global Clinical Operations. You will lead end‑to‑end trial optimization, drive digital capabilities, and oversee transformation programs across the global portfolio.

This senior leader partners with the Head of Global Clinical Operations, builds a high‑performing team, and delivers analytics, governance, and workforce planning to accelerate study delivery while

Qualifications

• Bachelor's degree required in Life Sciences, Engineering, Operations, or related field.
• Advanced degree (MS, MPH, PharmD, MBA, PhD) preferred.
• 15+ years of increasing leadership responsibility in Global Clinical Operations, R&D Operations, Clinical Development, or related functions within pharma, biotech, or CRO.

Responsibilities

• Lead a multi-year transformation roadmap to modernize Global Clinical Operations and elevate operational effectiveness.
• Identify enterprise-level opportunities to streamline clinical trial planning, site startup, enrollment, data collection, data cleaning, and closeout.
• Drive harmonization and standardization of GCO processes across regions, therapeutic areas, and CRO partners.
• Develop and oversee governance frameworks for clinical transformation initiatives, including prioritization, KPIs, and benefits realization.
• Collaborate with DTE to accelerate adoption of modern clinical technologies.
• Embed advanced analytics and predictive modeling to identify enrollment risks, monitor site performance, and optimize operational decision‑making.
• Oversee study and operational metrics, lead dashboard development.
• Lead GCO Resource Strategy and allocation.
• Drive the identification, implementation, and development of novel site and patient‑facing technologies, including support for end‑to‑end technology deployment and GMDA robotic process automation.
• Collaborate with external CROs, vendors, and strategic partners to ensure operational performance, consistency, and efficiency across outsourced studies.
• Build and lead a high‑performing Transformation/Operational Excellence team within GCO.
• Oversee change management strategies to ensure global adoption, behavior change, and sustained results.

Skills

Leadership

Strategic thinking

Analytics

Stakeholder management

Communication

Regulatory understanding

Education

Bachelor's degree

Advanced degree preferred

Job description

Vertex Pharmaceuticals LLC in the United States seeks an Executive Director of Performance Excellence & Business Transformation for Global Clinical Operations. You will lead end‑to‑end trial optimization, drive digital capabilities, and oversee transformation programs across the global portfolio.

This senior leader partners with the Head of Global Clinical Operations, builds a high‑performing team, and delivers analytics, governance, and workforce planning to accelerate study delivery while