Genomics Laboratory Operations Supervisor

Children's Hospital Colorado; Aurora (CO); On-site; USD 101,000 - 151,000; Full time

Benefits offered by this job

Competitive pay

Medical/dental/vision insurance

Life and disability insurance

Paid parental leave

403b employer match

Education benefit

Annual bonus program

Job summary

Children's Hospital Colorado is seeking a Genomics Laboratory Operations Supervisor to oversee the Genomics Operational Laboratory team and ensure high-quality, timely diagnostic reporting. The role collaborates with Clinical and Technical teams to implement workflow solutions in a matrixed environment.

The position is based in Aurora, with a day shift Monday–Friday and flexibility to support evenings and weekends as needed. Strong leadership and genomics expertise are essential.

Qualifications

• Bachelor's degree in Molecular Biology or a related field is required.

Responsibilities

• Oversees daily lab operations in the genomics facility to ensure quality and timely diagnostic reporting.
• Owns SLAs and TAT metrics, setting goals and reporting progress on core initiatives.
• Leads lab operations in coordination with Technical and Clinical teams, streamlining inter-team handoffs.

Skills

Leadership

Communication

Problem solving

Project coordination

Education

Bachelor's Degree in Molecular Biology or related field

Tools

Laboratory automation

Job description

Job ID 108128

Location Aurora

Position Type Regular

Regular/Temporary Regular

Job Overview

Summary

The Genomics Laboratory Operations Supervisor is an integral part of the Children's Hospital Colorado Precision Diagnostics Laboratory team. Oversees the Genomics Operational Laboratory team, which includes resolving issues, supporting operations and technical teams, and assisting in the implementation of solution workflows within a matrixed team environment. Contributes to fast and accurate outcomes while meeting patient care needs through collaboration with key partners and subject matter experts within the Center for Innovative Genomics.

Shift

Precision Diagnostics Laboratory

Monday - Friday, day shift

Requires flexibility to support weekend and evening staff as appropriate

ESSENTIAL FUNCTIONS

1. Oversees daily lab operations in the genomics facility to ensure strict adherence to quality guidelines and timely, accurate diagnostic reporting.
2. Owns operational service-level agreements (SLAs) and turnaround time (TAT) metrics, setting goals and reporting progress on core initiatives.
3. Leads lab operations in close coordination with distinct Technical and Clinical teams, streamlining inter-team handoffs across the matrixed organization.
4. Implements and sustains lab operations QA programs to maintain diagnostic accuracy and operational reliability across testing platforms.
5. Oversees physical lab equipment operations-including procurement, calibration, and maintenance-and collaborate with Innovation and Data Management for system performance and connectivity.
6. Ensures regulatory compliance within lab operations, integrating safety, productivity, and quality improvement initiatives across matrixed groups.
7. Drives operational workflow solutions and leads cross-departmental project logistics in partnership with Clinical, Technical, and executive leadership.
8. Develops operational staffing models and daily work plans aligned with organizational priorities and performance targets.
9. Supervises full employee lifecycle activities-including hiring, coaching, and performance management-for the lab operations team.
10. Champions continuous improvement and standardization of operational procedures in collaboration with Technical and Clinical partners.
11. Represents lab operations in leadership priorities, resolves operational escalations, and maintains high standards of service delivery.
12. Manages the lab operations budget and provides financial oversight to ensure alignment between expenditure and operational goals.

Minimum Requirements

EDUCATION - Bachelor's Degree in Molecular Biology or a related field

EXPERIENCE - Five (5) years' experience in a high complexity genomics clinical laboratory setting. Broad knowledge of genetics, molecular biology, and sequencing technologies. Experience with clinical data, electronic health records (EHR).

EQUIVALENCY - Combination of additional experience and education may substitute on a 1:1 year basis.

CERTIFICATION(S) - N/A

LICENSURE - N/A

Preferred Requirements

Ideal candidate would have previous people management experience and in-depth knowledge of complex genomic workflows. Deep expertise in complex genomics laboratory operations, testing methodologies, and end-to-end workflow management. Demonstrated success leading and developing laboratory personnel in fast-paced clinical and molecular diagnostic environments. Experience implementing and managing laboratory automation solutions and coordinating staffing and production schedules across multiple shifts to ensure operational excellence.

Salary Information

Pay is dependent on applicant's relevant experience.

Annual Salary Range (Based on 40 hours worked per week): $100,649.67 to $150,974.51

Benefits Information

Here, you matter. As a Children's Hospital Colorado team member, you will receive a competitive pay and benefits package designed to take care of your needs that includes base pay, incentives, paid time off, medical/dental/vision insurance, company provided life and disability insurance, paid parental leave, 403b employer match (retirement savings), a robust wellness program, and access to professional development tools, including an education benefit to help you advance your career.

As part of our Total Rewards package, Children's Colorado offers an annual employee bonus program that rewards eligible team members based on organizational performance. If organizational goals are met for the year, the bonus is paid out the following April.

Children's Colorado delivers annual base pay increases to eligible team members based on their performance over the previous year.

EEO Statement

It is our intention that all qualified applicants be given equal opportunity and that selection decisions be based on job-related factors. We do not discriminate on the basis of race, color, religion, national origin, sex, age, disability, or any other status protected by law or regulation. Be aware that none of the questions are intended to imply illegal preferences or discrimination based on non-job-related information. The position is expected to stay open until the posted close date. Please submit your application as soon as possible as the posting is subject to close at any time once a sufficient pool of qualified applicants is obtained.

Colorado Residents: In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of attendance at or graduation from an educational institution. You will not be penalized for redacting or removing this information.

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Estimated Close Date

10/22/2026