Genomics Data Scientist — Structural Variant Analysis

Broad Institute; Cambridge (MA); Hybrid; USD 120,000 - 180,000; Full time

Benefits offered by this job

Medical and dental coverage

401(k) retirement plan

Paid holidays and time off

Parental leave

Employee assistance program

Job summary

The Talkowski Laboratory in the Center for Genomic Medicine at Massachusetts General Hospital (MGH) and the Broad Institute of MIT and Harvard is seeking a highly motivated Computational Scientist to analyze sequencing data to identify structural variants in the human genome.

This hybrid role involves collaborating with biologists, computational biologists, and clinicians to translate models into experiments, develop pipelines, and visualize results for publications and IP.

Qualifications

• PhD required in a quantitative field.
• 2+ years of direct work experience.
• Experience with biological datasets, preferably large-scale genotyping and/or sequencing data.
• Proficiency in at least one modern programming language (Python or R).

Responsibilities

• Perform large-scale data analysis on genomics data and bulk sequencing data for collaborators.
• Mining of genetic databases and resources to evaluate loci for gene discovery.
• Conceive, implement and test genomics models; work with wet-lab researchers to translate these models into testable experiments; help analyze data from experiments.
• Evaluate and recommend new emerging data analysis tools.
• Create scientifically rigorous visualizations, communications, and presentations of results.
• Contribute to the generation of pipelines, protocols, publications, and intellectual property.
• Experience with publicly available genetic databases (eg GTEx, Roadmap, gnomAD, UCSC, GWAS catalog).
• Independent, highly motivated, and highly collaborative with the ability to work with multi-disciplinary teams.

Skills

Genomics data analysis

Cloud computing

Collaborative work

Education

PhD in quantitative discipline

Tools

Python

R

Job description

The Talkowski Laboratory in the Center for Genomic Medicine at Massachusetts General Hospital (MGH) and the Broad Institute of MIT and Harvard is seeking a highly motivated Computational Scientist to analyze sequencing data to identify structural variants in the human genome.

This hybrid role involves collaborating with biologists, computational biologists, and clinicians to translate models into experiments, develop pipelines, and visualize results for publications and IP.