Full-Stack Developer for Genomics Lab Systems

myDNA, Inc.; Houston (TX); On-site; USD 90,000 - 150,000; Full time

Job summary

myDNA, Inc. in Houston, TX seeks a Full-Stack Software Developer to design, develop, and support software for CAP/CLIA laboratory operations.

You will work across the stack (C#/ASP.NET Core, React, SQL Server) and collaborate with lab staff to deliver reliable data processing and instrument integration. The role requires strong fundamentals, experience with CI/CD, and the ability to apply SOLID principles; familiarity with genetics or genomics is a plus.

Qualifications

• Hands-on proficiency with ASP.NET Core, React, HTML/CSS, and RESTful Web API development.
• Strong SQL skills (primarily SQL Server, some PostgreSQL) and experience with Entity Framework.
• Working knowledge of software design principles (SOLID), object-oriented programming and design, system architecture, CQRS, and messaging systems such as RabbitMQ. Proficient with Git and continuous integration/deployment practices.
• Effective use of LLM-assisted development tools, including Claude Code, as part of the daily engineering workflow.
• Strong engineering fundamentals: the ability to decompose problems clearly, direct AI tooling toward a well-defined outcome, recognize flawed designs or subtle defects on sight, and reject output that does not meet quality standards.
• Strong troubleshooting and analytical skills, with the ability to collect, analyze, and summarize technical issues.
• Clear written and verbal communication, including the ability to explain complex technical topics to non-technical stakeholders.
• Demonstrated integrity, dependability, attention to detail, and a commitment to confidentiality and data security.
• Preferred: understanding of genetics, molecular biology, PCR, next-generation sequencing, laboratory automation, liquid handlers, and robotics.

Responsibilities

• Design, build, and ship full-stack solutions supporting laboratory operations using C#/ASP.NET Core, React/TypeScript, RESTful Web APIs, and SQL Server.
• Translate business and lab requirements into functional, maintainable solutions applying SOLID principles, appropriate design patterns, and CQRS where warranted.
• Build and integrate messagingbased workflows (RabbitMQ). Maintain and improve CI/CD pipelines and development tooling.
• Maintain code documentation and contribute to system architecture decisions.
• Use Claude Code and comparable AI development tools as a primary part of the daily workflow for implementation, refactoring, test authoring, and investigation.
• Critically review AI-generated output for correctness, security, and maintainability; reject or rework what does not meet standards.
• Participate in peer code review. Retain full accountability for all code that ships regardless of how it was produced.
• Investigate, triage, and resolve production and development issues affecting laboratory systems
• Collect, analyze, and summarize service issues; identify root cause and implement durable fixes.
• Support lab staff as a technical point of contact.
• Monitor system health and respond to incidents affecting sample processing or data flow.
• Confer with laboratory staff, scientists, and other stakeholders to gather and clarify requirements. Study systems flow, data usage, and work processes.
• Ask questions, make suggestions, and convey technical concepts clearly to non-technical audiences. Participate in UI/UX prototyping and solution validation.
• Protect operations by maintaining confidentiality of clinical and consumer genetic data and prioritizing security in all design and implementation decisions.
• Ensure changes to laboratory systems preserve data integrity and traceability consistent with CAP/CLIA requirements.
• Follow validation and change-control practices for regulated systems.

Skills

ASP.NET Core

React

RESTful Web APIs

SQL Server

PostgreSQL

Entity Framework

SOLID

CQRS

RabbitMQ

Git

CI/CD

AI tools

Problem decomposition

Security and data privacy

Communication

Education

Bachelor's degree in Computer Science, Software Engineering, or related field

Tools

Claude Code

RabbitMQ

Job description

myDNA, Inc. in Houston, TX seeks a Full-Stack Software Developer to design, develop, and support software for CAP/CLIA laboratory operations.

You will work across the stack (C#/ASP.NET Core, React, SQL Server) and collaborate with lab staff to deliver reliable data processing and instrument integration. The role requires strong fundamentals, experience with CI/CD, and the ability to apply SOLID principles; familiarity with genetics or genomics is a plus.