Executive Director, Portfolio & Program Management

Vertex Pharmaceuticals LLC; Boston (MA); On-site; USD 250,000 - 380,000; Full time

Job summary

Vertex is seeking an Executive Director of Portfolio & Program Management to lead global drug development and commercialization efforts across multiple disease areas. You will provide strategic and operational leadership to cross-functional teams in discovery, development, and market readiness, and mentor senior program managers.

Based in Boston with a hybrid work arrangement, you will drive resource optimization, organizational design, and governance representation, ensuring seamless

Qualifications

• Bachelor's in Life Sciences or related field
• 15+ years of experience including 7+ years in management of large, complex teams and programs
• Deep expertise in portfolio management, strategic planning, risk/resource management, and drug discovery/development

Responsibilities

• Provide strategic and operational leadership to cross-functional teams
• Mentor senior program managers
• Drive resource optimization and organizational design
• Represent the portfolio on governance and senior leadership forums
• Ensure integration of research, development and commercialization aligned with Disease Area Strategy Teams (DST)

Job description

Role: Executive Director of Portfolio & Program Management, leading global efforts across drug development and commercialization for multiple disease areas at Vertex.

Responsibilities include providing strategic and operational leadership to cross-functional teams, mentoring senior program managers, driving resource optimization and organizational design, and representing the portfolio on governance and senior leadership forums.

The role ensures integration of research, development, and commercialization aligned with Disease Area Strategy Teams (DST).

Requirements:

Bachelor's in Life Sciences or related field, 15+ years of experience including 7+ years in management of large, complex teams and programs, with deep expertise in portfolio management, strategic planning, risk/resource management, and drug discovery/development.

Skills needed include leadership of diverse teams, financial acumen, stakeholder collaboration, and biopharma knowledge across disciplines.

High-value specifics: experience in managing multiple disease areas, strategic growth initiatives, and operational excellence within a global biotech setting.

The position is hybrid, based in Boston (Seaport), with flexible remote work options and no explicit travel requirements.