Senior Director, DMPK Strategy & Leadership

Vertex Pharmaceuticals Inc (US); San Diego (CA); On-site; USD 233,000 - 349,000; Full time

Job summary

Vertex San Diego is seeking a Senior Director to lead the DMPK group, shaping project and portfolio plans and integrating activities across sites. The role demands strategic leadership, cross-functional coordination, and deep DMPK expertise to drive discovery and development of transformational therapies. Onsite at San Diego campus.

The candidate will mentor and manage personnel, oversee budgets, and collaborate with senior management to accelerate Vertex programs and approvals.

Qualifications

• Bachelor's degree with extensive experience in DMPK leadership roles.
• Strong managerial skills and ability to mentor junior scientists.
• Proven track record leading multi-disciplinary teams on R&D programs.

Responsibilities

• Serve as a DMPK functional lead on multidisciplinary project teams to advance Vertex drug discovery and development programs from early discovery to late development and regulatory submission.
• Collaborate with medicinal chemists to optimize drug candidates while avoiding liabilities.
• Prepare DMPK documents to support candidate nominations and regulatory filings.

Skills

DMPK leadership

Team management

Cross-functional collaboration

ADME knowledge

Regulatory awareness

Education

Bachelor's degree

Master's degree

Ph.D.

Tools

ADME tools

In vivo/in vitro assays

Job description

Vertex San Diego is seeking a Senior Director to lead the DMPK group, shaping project and portfolio plans and integrating activities across sites. The role demands strategic leadership, cross-functional coordination, and deep DMPK expertise to drive discovery and development of transformational therapies. Onsite at San Diego campus.

The candidate will mentor and manage personnel, oversee budgets, and collaborate with senior management to accelerate Vertex programs and approvals.