Director, Quantitative Pharmacology & Translational Science

Sarepta Therapeutics; Town of Florida (NY); Hybrid; USD 186,000 - 232,000; Full time

Job summary

Sarepta Therapeutics is seeking a Director of Quantitative & Clinical Pharmacology to lead pharmacometrics and clinical pharmacology deliverables from early to late-stage development, with emphasis on dose selection and model-based decision-making. The role is highly visible and team-facing, requiring collaboration across translational teams and regulatory bodies.

Ideal candidates will have a PhD with extensive clinical pharmacology experience, strong PK/PD modeling expertise, and proven ability

Qualifications

• PhD with 7 years in clinical pharmacology or pharmacometrics.
• Strong PK/PD modeling and regulatory experience.
• Experience with population PK modeling and data analysis.

Responsibilities

• Lead quantitative pharmacology strategies across development through product registration.
• Oversee clinical pharmacology expertise in study design, execution, and data reviews.
• Perform model-based analyses including population PK/PK-PD modeling and meta-analysis.
• Serve as functional lead for global regulatory strategies and HA engagements.
• Maintain leading-edge knowledge and disseminate findings at conferences and in publications.

Skills

PK/PD modeling

Clinical pharmacology

Regulatory interactions

NONMEM

R

CNS experience

siRNA experience

Education

PhD in Pharmaceutical Sciences or related field

Tools

NONMEM

R

Job description

Sarepta Therapeutics is seeking a Director of Quantitative & Clinical Pharmacology to lead pharmacometrics and clinical pharmacology deliverables from early to late-stage development, with emphasis on dose selection and model-based decision-making. The role is highly visible and team-facing, requiring collaboration across translational teams and regulatory bodies.

Ideal candidates will have a PhD with extensive clinical pharmacology experience, strong PK/PD modeling expertise, and proven ability