Director of Quantitative Pharmacology & Strategy

Sarepta Therapeutics; Washington (District of Columbia); Hybrid; USD 186,000 - 232,000; Full time

Job summary

Sarepta Therapeutics, a leader in genetic medicines, seeks a Director of Quantitative & Clinical Pharmacology to drive pharmacology strategies from early development through product registration. You will lead translational and translational PK/PD efforts, collaborate across teams, and influence regulatory engagements.

The role emphasizes model-based data analyses, regulatory strategy, and leadership in a high-visibility, team-facing environment. Hybrid role with on-site work in the U.S.

Qualifications

• PhD in Pharmaceutical Sciences with 7+ years in clinical pharmacology or pharmacometrics.
• Strong understanding of clinical pharmacology principles and regulatory interactions.
• Hands-on PK/PD modeling analysis experience; familiarity with NONMEM & R preferred.
• Excellent communication, multitasking, and collaboration skills.
• siRNA and/or CNS experience is preferred.

Responsibilities

• Lead quantitative pharmacology strategies across drug development from early to registration.
• Provide clinical pharmacology expertise in translational development, protocol prep, execution, data review, and study reports.
• Perform model-based analyses including population PK/PD, meta-analysis, and disease modeling to inform decisions.
• Serve as functional lead for global regulatory strategies and HA engagements.

Skills

PK/PD modeling

Regulatory interactions

Communication skills

Collaboration

NONMEM

R

CNS experience

Education

PhD in Pharmaceutical Sciences

Math/Engineering or related field

Job description

Sarepta Therapeutics, a leader in genetic medicines, seeks a Director of Quantitative & Clinical Pharmacology to drive pharmacology strategies from early development through product registration. You will lead translational and translational PK/PD efforts, collaborate across teams, and influence regulatory engagements.

The role emphasizes model-based data analyses, regulatory strategy, and leadership in a high-visibility, team-facing environment. Hybrid role with on-site work in the U.S.