Director of Quantitative PK/PD & Translational Strategy

Sarepta Therapeutics; Rhode Island; Hybrid; USD 186,000 - 232,000; Full time

Job summary

Sarepta Therapeutics invites applications for the Director of Quantitative & Clinical Pharmacology. Lead pharmacology deliverables from early to late-stage development, focusing on dose selection, PK/PD modeling, and translational approaches.

This highly visible role involves collaboration with cross-functional teams and global regulatory engagements. The position is hybrid, on-site at Sarepta facilities in the United States, with expected leadership across clinical pharmacology strategy and

Qualifications

• PhD in Pharmaceutical Sciences, mathematics/engineering or related field with 7+ years experience in clinical pharmacology or pharmacometrics.
• Strong understanding of clinical pharmacology principles and PK/PD modeling.
• Experience with regulatory interactions.

Responsibilities

• Drives development and execution of quantitative pharmacology strategies across all stages of drug development through product registration.
• Leads clinical pharmacology expertise in development strategies, protocol preparation, study execution and data review.
• Performs model-based analyses including population PK, PK/PD modeling and simulation, meta-analysis and disease modeling.

Skills

PK/PD modeling

Population PK

Regulatory interactions

Communication

Clinical pharmacology

Education

PhD in Pharmaceutical Sciences or related field

Tools

NONMEM

R

Job description

Sarepta Therapeutics invites applications for the Director of Quantitative & Clinical Pharmacology. Lead pharmacology deliverables from early to late-stage development, focusing on dose selection, PK/PD modeling, and translational approaches.

This highly visible role involves collaboration with cross-functional teams and global regulatory engagements. The position is hybrid, on-site at Sarepta facilities in the United States, with expected leadership across clinical pharmacology strategy and